Acute Kidney Injury and Gestational Diabetes in pregnancy – A prospective cohort study.

The aim of this study is to help better understand kidney function throughout pregnancy and blood sugar (glucose) levels late in pregnancy.

Acute Kidney Injury(AKI) is a sudden fall in kidney function. It can happen in pregnancy, during birth and after birth. AKI can cause problems for the pregnancy and the mother and in the longer term for a mother’s health. Currently, normal kidney function in pregnancy is unknown. This study will aim to more clearly define normal kidney function levels in pregnancy, thereby allowing a more accurate diagnosis of Acute Kidney Injury in the future.

Gestational diabetes is a type of diabetes that can develop during  pregnancy. Currently, gestational diabetes is diagnosed by a test called an Oral Glucose Tolerance TEST (OGTT), which is performed at around 24-28 weeks of pregnancy and is offered to mother’s who have risk factors for developing gestational diabetes. At times, whilst this result is normal, some women may go on to develop late onset of gestational diabetes and it may go undetected.

This study aims to look at normal levels of glucose in pregnant women after 32 weeks of pregnancy, using 2 types of test, with a view of finding best way to diagnose late onset gestational diabetes.

Women can choose to take part in both parts of the study, or the AKI aspect of the study.

The study commenced December 2019

Contact the Study Team: 

Telephone: 0117 414 6764

Email:  AKID@nbt.nhs.uk

Video Transcript

My name is Christy Burden I'm a Consultant Obstetrician here at Southmead Hospital and together with a team here at Southmead and the University of Bristol I'm undertaking the acute kidney injury and late diabetes in pregnancy study.

Why is the Study needed?

The study is needed as we currently do not know what normal kidney function levels are in pregnancy and we do not know what normal blood glucose levels are later on in pregnancy.  

This makes it difficult to diagnose problems with the kidney or acute kidney injury and makes it difficult to diagnose diabetes late in pregnancy after 32 weeks.

What will be involved if I take part in the study?

Being involved in the study will mean extra blood tests but where possible these will be taken alongside your routine pregnancy blood tests. It will also involve a glucose tolerance test. This is a test undertaken to diagnose diabetes in pregnancy.

What are the benefits and overall aims of the study?

Both problems with the kidneys and diabetes in pregnancy can cause complications for the pregnancy and can cause long-term health problems for women. The study aims to improve care for all women and babies by finding optimal way to diagnose these conditions.

Thank you very much for listening to this video. Please contact our research team if you want any more information regarding our study.

Contact the AKID Study team

Email: AKID@nbt.nhs.uk

Telephone: 0117 4146764