DopaCon Study

Parkinson's disease and Huntington's disease cause a whole host of symptoms, but the cognitive symptoms are much less studied than the motor ones. We are aiming to investigate the role of dopamine in memory deficits seen in Parkinson's and Huntington's disease. Parkinson's Disease patients have lower levels of dopamine in the brain, and take medications to raise these levels. By varying when they take their doses we can see the effects of high and low levels of dopamine on specific stages of memory.

Huntington's disease patients and healthy older adults will complete one testing session, lasting about 1.5 hours, and will involve several memory tests and questionnaires. People with Parkinson's disease will come in for three sessions: one screening visit (about 30 minutes) and then two 90 minute visits. For one of these 90 minute visits we will ask them to come off their Parkinson's disease medications before coming in, so we can see the effects of low levels of dopamine on the cognitive tests.

Participants

We are recruiting three groups for this study; people with Parkinson's Disease, people with Huntington's disease, and older adults without any neurological conditions. If you fall into one of these categories and wish to take part in the study, please contact us on john.grogan@nbt.nhs.uk or 0117 4148186.