ReMemBr Group Publications


  • Shaikh, N. & Coulthard, L. 2018. 'Nap‐mediated benefit to implicit information processing across age using an affective priming paradigm.' Journal of Sleep Research. [link]
  • Pennington, C., Davey, K., Coulthard, L., ter Meulen, R. & Kehoe, P. 2018. 'Tools for testing decision-making capacity in dementia.' Age and Ageing. afy096. [link]
  • Colenutt, J., McCann, B., Knight, M. J., Coulthard, E. & Kauppinen, R. A. 2018. 'Incomplete Hippocampal Inversion and Its Relationship to Hippocampal Subfield Volumes and Aging.' Journal of Neuroimaging. 28, 4, p.422-428. [link]
  • Coulthard, L. & Love, S. 2018. 'A broader view of dementia – multiple co-pathologies are the norm.' Brain, 141, 7, 1894-1897. [link]
  • Knight, M., Wearn, A., Coulthard, L. & Kauppinen. 2018. 'T2 relaxometry and diffusion tensor indices of the hippocampus and entorhinal cortex improve sensitivity and specificity of MRI to detect amnestic mild cognitive impairment and Alzheimer’s disease dementia.' Journal of Magnetic Resonance Imaging. 


  • Kehoe, P., Ben-Shlomo, Y., Howden, B., Lane, J. A., Coulthard, L., Blair, P., Horwood, J., Selman, L. & Clement, C. 2017. 'The Rationale and Design of the Reducing Pathology in Alzheimer’s Disease through Angiotensin TaRgeting (RADAR) Trial'. Journal of Alzheimer's Disease. 61, 2, 803-814. [link]
  • Dillon, S.E., Tsivos, D., Knight, M., McCann, B., Pennington, C., Shiel, A.I., Conway, M, Newson, M.A., Kauppinen, R.A., & Coulthard, E.J. 2017. ‘The impact of ageing reveals distinct roles for human dentate gyrus and CA3 in pattern separation and object recognition memory.’ Scientific Reports, 7  (1), 14069. [link]
  • Bourbon-Teles, J, Bells, S, Jones, DK, Coulthard, E, Rosser, A & Metzler-Baddeley, C, 2017, ‘Myelin breakdown in human Huntington's disease: Multi-modal evidence from diffusion MRI and quantitative magnetization transfer’. Neuroscience. [link]
  • Grogan, J.P., Tsivos, D., Smith, L., Knight, B.E., Bogacz, R., Whone, A., Coulthard, E.J. (2017). Effects of dopamine on reinforcement learning and consolidation in Parkinson’s disease. eLife, 6, e26801. [link]
  • Tales, A, Burholt, V, Nash, P, Bichard, J-A, Clayton-Turner, A, Coulthard, L & , 2017, ‘Dementia-friendly public toilets’. Lancet, vol 390., pp. 552-553 [link]
  • Coulthard, L & Knight, M, 2017, ‘Refining Alzheimer’s disease diagnosis with MRI’. Brain, vol 140., pp. 524-526 [link]


  • Knight, M., McCann, B., Tsivos, D., Dillon, S., Coulthard, E. & Kauppinen, R. (2016). Quantitative T2 mapping of white matter: applications for ageing and cognitive decline. Physics in Medicine and Biology. 61, 15, 5587 [link]

  • Sharma, K., Davis, T. & Coulthard, E. (2016). Enhancing attention in neurodegenerative diseases: current therapies and future directions. Translational Neuroscience, 7(1), pp. 98-109. [link]

  • Al-Sari, U, Tobias, J, Archer, H & Clark, E, 2016, ‘Do subjective memory complaints predict falls, fractures and healthcare utilization? A two-year prospective study based on a cohort of older women recruited from primary care’. International Journal of Geriatric Psychiatry. [link]

  • Greenan, Caroline, et al. "A randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT): study protocol." Trials 17.1 (2016): 1. [link]

  • Knight, M. J., McCann, B., Tsivos, D., Coulthard, E., & Kauppinen, R.A. (2016). Quantitative T1 and T2 MRI signal characteristics in the human brain: different patterns of MR contrasts in normal ageing. Magnetic Resonance Materials in Physics, Biology and Medicine, 1-10. [link]
  • Knight, M., Wood, B., Kauppinen, R., & Coulthard, E. J. (2016). Magnetic Resonance Imaging to Detect Early Molecular and Cellular Changes in Alzheimer’s Disease. Frontiers in Aging Neuroscience, 8, 139. [link]


  • rCBF SPECT for detection of frontotemporal dementia in people with suspected dementia; Archer HA, Smailagic N, John C, Takwoingi Y, Coulthard EC, Cullum S. Cochrane Database of Systematic Reviews 2015, Issue 6.  [link]

  • Knight, M. J., Wood, B., Couthard, E., & Kauppinen, R. (2015). Anisotropy of spin-echo T2 relaxation by magnetic resonance imaging in the human brain in vivo. Biomedical Spectroscopy and Imaging, 4(3), 299-310. [link]

  • Archer, H.A., Newson, M.A., & Coulthard, E.J. (2015). Subjective Memory Complaints: Symptoms and outcome in different research settings. Journal of Alzheimer's Disease, 2015; 48(S1), S109-S114. [link]

  • A defect in the retromer accessory protein, SNX27, manifests by infantile myoclonic epilepsy and neurodegeneration. Neurogenetics. Damseh, N., Danson, C.M., Al-Ashab, M., Abu-Lindeh, B., Gallon, M., Sharma, K., Yaacov, B., Coulthard, E., Caldwell, M.A., Edvardson, S., Cullen, P.J., & Elpeleg, O. 2015 Jul;16(3):215-21. [pubmed] [link]

  • Pennington, C., Newson, M., Hayre, A., & Coulthard, E. Functional Cognitive Disorder: What is it and what to do about it? Practical Neurology. 2015 Dec;15(6):436-44. [link]

  • Pennington, C., Hayre, A., Newson, M., & Coulthard, E. Functional Cognitive Disorder: A common cause of subjective cognitive symptoms. Journal of Alzheimer's Disease. 2015;48(S1):S19-S24. [link] [researchgate]

  • Haworth, J., Phillips, M., Newson, M., Rogers, P., Torrens-Burton, A., Tales, A. Measuring Information Processing Speed in Mild Cognitive Impairment: Clinical vs Research Dichotomy. Journal of Alzheimer's Disease. 2016 Jan; 51(1): 263-275. [link]

  • Grogan, J.P., Bogacz, R., Tsivos, D., Whone, A., & coulthard, E.J. (2015). Dopamine and consolidation of episodic memory: timing is everything. Journal of Cognitive Neuroscience. [link]

  • Archer, H.A., Smailagic, N., John, C., Holmes, R.B., Takwoingi, Y., Coulthard, E.J., Cullum, S. Regional Cerebral Blood Flow Single Photon Emission Computed Tomography for detection of Frontotemporal dementia in people with suspected dementia. Cochrane Database of Systematic Reviews 2015, Issue 6. [link

    • This is a systematic Cochrane review that aims to assess whether a type of brain scan, SPECT, helps in the diagnosis of frontotemporal dementia.

  • Broadfoot, J.R., Archer, H.A., Coulthard, E., Appelman, A.P.A., Sutak, J., Braybrooke, J.P., & Love, S. (2015). Paraneoplastic tumefactive demyelination with underlying combined germ cell cancer. Practical Neurology, 0, 1-5. [link]

    • ​A case report on a patient with cognitive problems related to malignancy.

  • Wood, B., Knight, M.J., Tsivos, D., Oliver, R., Coulthard, E., & Kauppinen, R.A. 2015 'Magnetic resonance scanning and segmentation procedure at 3T for volumetry of human hippocampal subfields. Biomedical Spectroscopy and Imaging, vol 4., pp. 197-208 [link]

    • This is a technical paper describing a protocol looking in detail at the hippocampus, an area of the brain affected early in Alzheimer's disease, using MRI scanning.


  • Metzler-Baddeley, C, Canterac, J, Coulthard, EJ, Rossor, A & Baddeley, RJ 2014, ‘Improved Executive Function and Callosal White Matter Microstructure after Rhythm Exercise in Huntington’s Disease’. Journal of Huntington's Disease, vol 3., pp. 273 [Link]

    • This paper looked at the effectiveness of rhythm exercise on executive function in patients with Huntington's disease. Patients completed two months of training and showed improvements in executive function along with changes in the connections between different brain regions.

  • Archer HA, Panopoulou A, Bhatt N, Edey AJ, Giffin NJ.  Mesothelioma and anti-Ma paraneoplastic syndrome; heterogeneity in immunogenic tumours increases.  Pract Neurol. 2014 Feb;14(1):33-5 [Link] [PubMed]

    • A case report on mesothelioma (a form of cancer).


  • Shaikh, NN & Coulthard, EJ. 2013, ‘Memory consolidation — Mechanisms and opportunities for enhancement’. Translational Neuroscience, vol 4., pp. 448 [Link]

    • A review of memory consolidation (the process of storing memories long-term), including the potential for enhancing consolidation.

  • Coulthard, EJ, Archer, HA, Smailagic, N, John, C, Giannakou, A, Holmes, RB & Cullum, SJ. 2013, ‘rCBF SPECT for detection of frontotemporal dementia in people with suspected dementia’. Cochrane Database Syst Rev. [Link]

    • A review of the effectiveness of SPECT (a clinical neuroimaging technique) on brain bloodflow to diagnose frontotemporal dementia.


  • Coulthard, EJ, Bogacz, R, Javed, S, Mooney, L, Murphy, G, Keeley, SA & Whone, AL 2012, ‘Distinct roles of dopamine and subthalamic nucleus in learning and probabilistic decision making’. Brain : a journal of neurology, vol 135., pp. 3721-3734 [Link]

    • This work was carried out on healthy older people and people affected by Parkinson's disease. In this paper we showed that a tiny area of the brain called the subthalamic nucleus is important when we need to use several pieces of information to make a decision. In other words, this brain area helps us to reason well when we need to take more than one thing into account. In this paper we also showed that dopamine improved consolidation of memory after initial learning. This finding led to much of our current work investigating the role of dopamine in memory.

ReMemBr Group Publications