Movement Disorders Research Current Projects


Principal Investigator: Dr Alan Whone
Investigators: Louise Gethin – Research Nurse

Tracking Parkinson's is the world's largest ever in-depth study of people with Parkinson's.
Launched in 2012, Tracking Parkinson's aims to study thousands of people to learn more about how the condition develops and progresses. Ultimately, the aim is to develop biomarkers that will allow us to diagnose and monitor Parkinson's accurately. They have recruited 2,240 people across 70 study centres UK-wide.
This study has been extended to continue monitoring those participants currently recruited. The aim is to extend the study up to 9 years.
This study is run by Southern General Hospital, Glasgow and is funded by Parkinson’s UK
Further study information can be found here:


Principal Investigator: Dr Alan Whone
Investigators: Dr Michal Rolinski

PD-COMM is a multi-centre study Randomised Controlled Trial to Compare the Clinical and Cost Effectiveness of Lee Silverman Voice Treatment Versus Standard NHS Speech and Language Therapy Versus Control in Parkinson’s Disease
This study is looking into whether Speech and Language Therapy (SLT) helps people with speech or voice difficulties as a result of their Parkinson’s disease. Currently there is little evidence as to whether SLT benefits people with Parkinson’s disease. Two different types of SLT are currently offered by the NHS for people with Parkinson’s: standard NHS SLT or Lee Silverman Vocal Treatment (LSVT). Once we have completed this study, we will be able to use the results to say what is the best way Speech and Language Therapy can help Parkinson’s disease patients.

This study is run by the University of Birmingham through the Birmingham Clinical Trials Unit and is funded by the National Institute of Health Research’s Health Technology Assessment (HTA) Programme. Here at Southmead, the study intervention is conducted by our Speech and Language Therapy team and supports their strategy of implementing research which ultimately impacts and improves outcomes for people of all ages with communication impairments.

Further study information can be found here:



Principal Investigator:  Dr Alan Whone
Investigators: Dr Mihaela Boca, Dr Michal Rolinski

MAPS-PD is a single-centre, investigator led, pilot study investigating motor adaptation in Parkinson’s disease, REM-sleep behaviour disorder patients and healthy controls using reaching and walking tasks.
The purpose of this small study is to assess the way people with Parkinson’s and REM-sleep behaviour disorder adapt their movements during reaching and walking tasks when compared to healthy volunteers. We will do this by gathering data on the time taken and the accuracy of movement in the subjects' adaptation to simple changes in the external environment.

This study is run by North Bristol NHS Trust


Principal Investigator: Dr Konrad Szewczyk-Krolikowski

CHARMED-MS is an observational study looking at the characteristics of tremor in people with Multiple Sclerosis (MS) and essential tremor referred to the Movement Disorders team for consideration of Deep Brain Stimulation (DBS). Study participants will have their arm movements and tremor measured using surface worn sensors in order to identify different tremor characteristics. It is expected that this study will help to identify types of tremor that best respond to DBS and in turn help to inform patient selection for people with MS and tremor referred for DBS

Study end date: 31 January 2022