Research Fund Awards - 2016

Women & Children

Dr Katie Cornthwaite

Award  £19,631 : Development of simulation training for difficult delivery of an impacted fetal head at caesarean section 

Over one quarter of women in the UK undergo a Caesarean birth. This sometimes occurs when women are fully (10cm) dilated, also known as the second stage of labour. These technically difficult births are associated with significant risks to mother and baby. There is no established consensus regarding which method is safest and most effective in these situations. Lack of knowledge and training can lead to delays in the birth and increased risk of complications.
This project aims to develop a training program, where maternity staff can learn in simulation and apply these skills in clinical practice leading to greater confidence in maternity staff and improvements in outcomes for mothers and babies.

Women & Children

Danya Bakhbakhi

Award £7,582 : Exploring parental involvement in deciding which core outcomes matter to parents in stillbirth studies

Care for parents following a stillbirth is not always as good as it should be. Until recently, research on how to improve care for bereaved parents had been neglected.
Currently studies evaluating potential care and pathways after a stillbirth measure many different outcomes. Therefore, when the studies have finished, their results cannot be directly compared or combined.  We intend to develop a Core Outcome Set (COS) for care and treatments following a stillbirth to address this issue.  This will help patients, clinicians, and guideline developers make the best use of available research in the future, making research and the use of research funding more efficient.  But also ensures rapid progress in the field of stillbirth research

Renal & Transplant

Dr Phillippa Bailey

Award £4,160 : Socioeconomic position and organ donation after death in England
There is a clear shortfall between the number of individuals requiring a transplant and the number of deceased-donor organs available for transplantation. Some people who die in hospital are suitable for possible organ donation, described as ‘potential organ donors’. Of these people who are suitable for organ donation, only some will actually donate their organs to become ‘actual organ donors’.
The proposed study will aim to address the question ‘Is socioeconomic position associated with the likelihood of organ donation after death?’ To address this question we will analyse two national datasets of routinely collected hospital data from 2008 to 2012 inclusive. We will aim to understand whether certain socioeconomic groups are more or less likely to donate their organs after their death.

Rheumatology

Dr Paul Creamer

Award : £13,650 : Understanding patient perceptions of dose reduction for biologic therapy in inflammatory arthritis: a qualitative study

About 12 years ago a new class of drugs was introduced for the treatment of some forms of arthritis including rheumatoid arthritis and ankylosing spondylitis. These drugs, sometimes called “biologic therapies” are quite different as they are “designer drugs” specifically developed to block certain parts of the immune system. They have been extremely helpful, especially for patients who have tried and failed other traditional therapies.  Unfortunately, as with all drugs, these new drugs have potential side effects including local reactions, infections and possibly a small rise in the long-term risk of cancer.  We currently have very good advice on when and how to start these drugs but much less is known on when we should stop them.
The aim of this study is to undertake detailed interviews with a selection of patient’s attending the Rheumatology Department at NBT and UHB.  By doing this we will understand more about patient’s perceptions and concerns about reducing the dose of drug.  We believe that involving patients and understanding the patient perspective is vital for our continued delivery of the best possible service and treatment options.

 

NeoNatal

Dr David Odd

Award £3193 : Educational Trajectories after Preterm Birth

Many studies have shown that babies born early can struggle at school, and this early delivery can have important impacts on their educational and social successes. Some of these problems may be due to brain damage that occurs around birth, or during the neonatal period, but often it is unclear why these children appear to perform less well than others. The Bristol based study (Avon Longitudinal Study of Parents and Children study (ALSPAC) /Children of the 90’s) recruited over 14,000 children in the Avon region and allows us to look in detail to how these vulnerable infants grow and develop, and investigate if there are patterns to their educational needs which can help target support for them.
The aim of this work is to compare the early (e.g. Key Stage 1) educational outcome of babies born early and see if the way they perform at school, as they grow, can help us identify any specific educational needs and when the best point to provide special support may be.