Bristol Genetics Laboratory (BGL) offers a comprehensive service for cytogenetic testing of oncology samples; primarily for haematological malignancy but also for a range of solid tumour and other referrals.
What is Cytogenetics?
Cytogenetics is the study of the structure and function of chromosomes. We analyse chromosomes by G-banded metaphase karyotyping, comparing the unique banding pattern of each chromosome pair. Changes in the number or structure of chromosomes can lead to serious problems, such as cancer. A normal cytogenetic result does not exclude the presence of an undetected or cryptic disease related clone.
Chromosome analysis is frequently supplemented by:
- FISH (Fluorescence in situ Hybridisation)
- Molecular pathology investigations
When do we analyse chromosomes?
- for new patients
- classification of the disease
- diseases where specific disease related chromosome rearrangements are known
- for risk stratification
- follow-up studies for cases of relapse
- where previous cytogenetic abnormalities have been documented
- transplant and treatment success
- Patients in clinical trials
For a full list of disease tests, please see the A-Z of Services
Please also see the Sample Requirements
Last updated: 12th December 2016