Understanding Vestibular Schwannomas (VS)

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This page explains what a vestibular schwannoma (VS) is and what it might mean for you. Your doctors and nurses can tell you more and answer your questions. At the end, there is information about groups that can help.

What is a VS?

A vestibular schwannoma, also called an acoustic neuroma, is a non-cancerous tumour. It grows on the balance nerve that
connects the inner ear to the brain. This nerve sits very close to the hearing nerve and to the facial nerve, which helps you move your face.
Because the tumour is benign, it does not spread to other parts of your brain or body.

What causes a VS?

The tumour starts in Schwann cells, which are cells that cover nerves and help them send messages. Most of the time, doctors do not know why the tumour appears. A very small number of people with a rare condition called NF2 can get tumours on both sides of the head.

Symptoms

A VS usually grows very slowly, so symptoms may take months or years to appear. Some people do not notice any symptoms at first.
As the tumour grows, it may press on nerves nearby. This can cause hearing loss, ringing in the ear, dizziness, or balance problems. If it grows more, it may cause numbness in the face, weakness in the face, pain around the ear, or trouble walking steadily.

Very large tumours can block the normal flow of fluid around the brain and cause something called hydrocephalus. This can lead to strong headaches, sickness, vision problems, nausea, memory troubles, wobbliness, or feeling extremely sleepy.

If you suddenly lose hearing in one ear or suddenly notice weakness on one side of your face, you should get urgent medical help from your doctor or go to an Emergency Department. Steroid medicine may help if it is given quickly.

Diagnosis and tests

A VS is sometimes first noticed after an unusual hearing test result. You may have more hearing tests to check how well you hear sounds and speech. Sometimes, a VS is found on a scan performed for a different reason altogether. 

Most VS tumours are found using an MRI scan. This scan is safe and does not hurt. If someone finds small spaces uncomfortable, they may have be offered a mild sedative. 

Some people cannot have an MRI because of metal in their body, such as a pacemaker. In that case, a CT scan can be used to make the diagnosis.

The care team (MDT)

Your care is planned by a group of specialists called the MDT (Multi-Disciplinary Team). This team includes many experts, such as brain surgeons, ENT surgeons, radiotherapy doctors, scan specialists, specialist nurses, and a coordinator. They look at your symptoms, age, your general health, the size of the tumour, and how fast it is growing. Your consultant will talk to you about what the team suggests.

Treatment options

Watch and wait

If the tumour is small/medium and not causing problems, you may not need treatment straight away. Instead, you may have regular MRI scans to check whether it is growing.

Radiotherapy

If the VS is growing, or a reasonable size when it is discovered, the MDT may suggest radiotherapy. Radiotherapy uses powerful energy beams to damage the tumour cells, so they stop growing. A common method is called Gamma Knife, which many people have in one day, although sometimes treatment takes place over several days or weeks.

Radiotherapy for VS is done at the Bristol Oncology Centre. If the MDT suggests radiotherapy, you will be seen by the Oncology team at the Bristol Haematology and Oncology Centre. The Oncology team will discuss the pros and cons of radiotherapy in more detail.

Surgery

Surgery may be needed depending on the size and position of the tumour, and the symptoms you have. This is a significant operation and needs to be planned carefully. 

The tumour can be removed through the bone or skull behind the ear. Before surgery, you will meet the surgeon to talk about your symptoms, why surgery is recommended, what will happen during the operation, how long recovery might take, and any risks.

Surgery for VS is mostly non-urgent, however large tumours causing hydrocephalus require more urgent surgery. You will have time to think about your decision. The aim of the surgery is to remove as much of the tumour as possible while protecting the nerves nearby, especially the facial nerve. Sometimes a thin layer of the tumour is left behind to protect the nerve, and this area is checked later with MRI scans.

Before your surgery, you will go to a clinic where you will have an examination, blood tests, an ECG, and possibly other tests. You can ask more questions there. On the day of the surgery, you will see your surgeon and the anaesthetist again.

The operation usually takes between 8 and 12 hours. After surgery, you will spend a few days in a high-dependency unit before moving to a normal ward. Most people stay in hospital for about a week to 10 days. Feeling dizzy, sick, or unsteady is common for a while. A physiotherapist can help you learn exercises to improve your balance.

Most people lose hearing in the operated ear, and this usually cannot be fixed. A hearing therapist or audiologist can help with advice and equipment if needed. Weakness in the facial muscles may occur after large tumours are removed. This can make it hard to blink or close one eye, which may become dry. You might need eye drops, gels, or eye protection at night. Physiotherapists can show exercises to help the facial muscles and may arrange more therapy if needed.

In some rare cases, facial weakness can be more severe or last longer. Speech or swallowing can also be affected, and a speech and language therapist can help. Sometimes a feeding tube is needed for a short time.

Serious problems such as infection, meningitis, leaking brain fluid, brain damage, or hydrocephalus are rare. The risk of serious neurological or life-threatening complications are very rare. You should get urgent medical help if you notice clear fluid coming from your nose or ear, a fever, a stiff neck, headaches that get worse, vision problems, new facial weakness, or a wound that looks red or swollen.

Hearing loss

Hearing loss in one ear is the most common symptom of VS.

The other ear is not affected. This can make it harder to know where sound is coming from or to hear when there is background noise. Hearing loss caused by VS is usually permanent. It may continue to worsen in the future, even if the VS is not growing. An audiologist may suggest a hearing aid, a CROS device, or a bone-anchored hearing aid.

Tinnitus

Tinnitus means hearing a sound, such as ringing or buzzing, when nothing outside your body is making the noise. It is very common and can be worse in the ear affected by the VS. Tinnitus UK is a national charity that offers support and advice. They have an excellent website with lots of information (tinnitus.org.uk). Many audiology teams can also help with tinnitus.
 

Dizziness

A VS can affect the balance system in the ear, which may make you feel unsteady, especially when turning quickly or doing complicated movements. Some people have short spinning feelings called vertigo. Staying active is usually the best way to get better because it helps your body learn to balance again. Physiotherapists can teach exercises that help your balance recover. These can feel difficult at first, but most people improve over time. If dizziness suddenly becomes very bad, you should see a doctor. 

Sudden changes

Sometimes symptoms can suddenly get worse. If you suddenly lose hearing in one ear within three days or notice new facial weakness, you should see your GP or go to the Emergency Department on the same day. Steroid medicine may help if it is given early. Very large tumours can cause hydrocephalus, which is serious. Strong headaches, sickness, vision problems, memory trouble, or feeling very sleepy should be checked urgently.

Driving

You can drive again once you have fully recovered from surgery. You do not need to tell the DVLA, but you should tell your insurance company. You can ask your GP to help check that you are ready to drive. You may need to inform the DVLA if you have sudden, disabling, or recurrent dizziness.

 

Follow-up and recovery

Follow-up

Two to three months after surgery, you will return to the Skull Base Clinic for a check-up. You will also have a phone call with a Brain Tumour Support Worker about four weeks after going home. Many people have an MRI scan around three months after surgery, and you may need more scans if a small piece of the tumour was left behind. Long term support for hearing loss, tinnitus and balance problems can be provided by your local audiology team.

Recovery

Everyone recovers at a different speed. It is normal to feel very tired for several weeks after surgery. It helps to rest and slowly increase your activity over time. Many people need between three and six months off work to recover fully. If you have questions while you recover, the specialist nurse team can support you.

Date published: 30 June 2026 Review due: 30 June 2029 PI number: BFT003103

Leech therapy

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Introduction 

This information aims to answer some of the questions you may have about leech therapy. It explains the benefits, risks and alternatives of the procedure, as well as what to expect. 

If you have any questions or concerns, please do not hesitate to speak to one of the team caring for you. 

What are leeches and why are they used? 

Medicinal leeches are worms that suck and feed on blood. Their scientific name isHirudomedicinalisand Hirudoverbana. 

They have been used in medicine since the dawn of civilization,and recently there has been an increase in using leeches in reconstructive surgery. 

Leeches help to improve blood circulation in congested flaps or other tissue (such as an amputated finger that has been re-attached). 

How do they work? 

They latch to the skin with their tiny sharp teeth and their saliva contains a number of chemicals to aid them to suck and feed on blood. These chemicals include a local anaesthetic (to reduce pain) and blood thinners. 

Am I going to feel pain? 

Leech bites are typically painless because they have a local anaesthetic in their saliva. 

What are the benefits of leeches? 

In some cases where blood is congested and needs to be released release, leech therapy can help. 

Leeches can suck a large amount of blood relative to their body. Each leech can suck between 5 - 15 millilitres of blood in one feed. The bite mark can still bleed a little for up to 72 hours after the leech has detached, due to the blood thinners in the leech’s saliva which act only locally (on this area). This often resolves the problem with the circulation. 

Why was I chosen to be offered leech therapy? 

You have been offered leech therapy because we believe it would be the best treatment for your congested flap or other tissue. 

If there is not enough outflow of blood in this area and it is left untreated, it may lead to the flap or other tissue dying. 

What are the side effects and risks of leeches? 

  • Leech therapy is often associated with bleeding and commonly transfusion of blood / blood products during or after treatment. We will do blood tests every day to see if you need a blood transfusion. Leech therapy will not be started unless you are comfortable with thepossibility of blood transfusion. If you cannot or would not like to have blood transfusion, leech therapy will not be started. 
  • Leeches contain bacteria that sometimes cause infection. You will be started on an oral antibiotic to prevent this. The leech site will be monitored daily by the nurses and doctors. If you are allergic to any of the antibiotics started, please tell your medical team and you will be offered analternative antibiotic. 
  • Rarely, people may develop an allergic reaction to leeches. Leeches will not be used on you if you have any history of allergic reactions to them. 
  • Leech therapy may not be suitable if you have an immunodeficiency, bleeding disorders, heart problems, unless you and your consultant decide the benefits of using leeches outweighs the risks. 
  • eeches can sometimes migrate into dressings. Nurses will be closely looking after your leeches when they are used. 
  • It has been reported that some patients may have some psychological difficulties in dealing with leeches. If that is the case, our psychologists will be happy to offer their advice and help. 
  • Leeches in our department are never used between patients and are disposed of humanely and safely. Transmission of blood borne diseases is not a risk. 

Is there an alternative? 

Usually, if your doctor has decided to use leech therapy, it means it is the last resort to save your congested flap. If you choose to do nothing, blood may clot and prevent blood flow to the flap. This may lead to some or all the tissue dying and the flap will need to be removed. 

How do I give my consent? 

If you agree to go ahead with leech therapy, you will be asked to sign a consent form. 

What happens next? 

  • The nurse will clean the area and apply the leech. Sometimes the nurse will scratch the area to allow the leech to latch on.  
  • We will closely monitor the leeches and the area to check its response to treatment. The number of leeches used and how often we use them depends on the response. 
  • You will have daily blood tests. 
  • After each feed, leeches are disposed of safely and according to trust policy.  

What do I need to do? 

You will be asked to stay in a position that allows the leech therapy to work. 

You will be asked to avoid eating or drinking any caffeine- containing food or drinks (such as tea; coffee or cola) and to avoid the use of nicotine-containing products (such as cigarettes or nicotine replacement therapy), during your hospital stay. 

What do I need to be aware of after the leech therapy finishes? 

There are no specific aftercare instructions. However, if you feel unwell (for example, if you have a fever, increased redness, or pain in the area) please let the teamcaring for you know. 

Contact us 

If you have any questions or concerns about leech therapy, please talk to your clinical team, including your plastic surgeon, plastic clinical nurse specialist, nursing team or pharmacy staff. 

You can also speak to the ward sister or nurse in charge of Ward 33A on 0117 414 3100. 

Feedback 

If you would like to give us any feedback on your care or treatment please see this page Feedback | North Bristol NHS Trust 

Further information 

  • For online information about health visit nhs.uk 
  • NHS 111 offers medical help and advice from fully trained advisers supported by experienced nurses and paramedics. Available over the phone 24 hours a day. 
  • References available on request. 

© North Bristol NHS Trust. This edition published June 2026. Review due June 2029. NBT002763 

Long term azithromycin for adults with respiratory conditions

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Azithromycin prophylaxis

Azithromycin is an antibiotic. It can be used for a few days to treat certain infections. 

Azithromycin can also be used for a long period (months) to help protect people with some types of lung disease. This leaflet is about long term use of azithromycin for people with lung disease. This is called azithromycin prophylaxis.

Why have I been prescribed long-term azithromycin (azithromycin prophylaxis)?

You have been prescribed long term azithromycin to prevent chest infections and to improve your chest symptoms. 

Azithromycin does not work for everyone with lung disease but it may help you in two ways:

  1. it is an antibiotic and can kill some of the bugs (bacteria) that could cause chest infections
  2. it can reduce inflammation in the airways so it can help to relieve cough, sputum production, and breathlessness

Azithromycin used in this way, is “off-label” and is different to what described in the patient information leaflet that comes with the medication. Using it like this is endorsed by the British Thoracic Society. It is important to take the medication as your Respiratory Consultant has advised.

What do I need to know before I take azithromycin?

Do not take this medication if you are allergic to azithromycin, any of its ingredients, or any other macraolide antibiotic such as erythromycin or clarithromycin.

To make sure azithromycin is the best choice for you your consultant/respiratory nurse specialist will:

  1. ask you to provide phlegm samples, to check for non tuberculosis mycobacterium. If this bacteria is present, azithromycin cannot be used
  2. check your heart’s rhythm using an electrocardiogram (ECG); this is also known as a heart tracing
  3. take some blood tests and check your liver function before and one month after starting azithromycin

Azithromycin will not work if you are a current smoker. You should have stopped smoking completely before we prescribe it. Azithromycin can also make you more prone to sunburn and we recommend using sun block on hot sunny days or when on holiday. Speak to your doctor or pharmacist to see how we can support you to stop smoking.

How long will I be on this medicine? 

Usually for 6 to 12 months. This gives enough time for you and your doctor to see if it works for you. If you get less chest infections or have less cough, sputum production, and breathlessness then it may be useful to stay on it for longer.

What are the common and important side effects? 

Most people have no troublesome side effects.

  • Some people have tummy upset, feeling sick (nausea), getting sick (vomiting). 
  • Some people get light headedness, dizziness, or fast heart rate (palpitations) and may need to get their ECG (heart tracing) checked. 
  •  A small number of people get jaundice (yellow colour of the skin or whites of your eyes) or itching because of liver upset. 
  • A very small number of people get hearing problems (ringing in the ears or poor hearing). If you notice a change in your hearing, it is important you stop the medication and seek medical advice 
  • A very small number of people get poor balance (unsteady on their feet). 
  • Some people get diarrhoea caused by overgrowth of a bacteria known as C diff (Clostridioides difficile). 

If you think azithromycin is causing you troublesome side effects at any time you should talk to your doctor. You may need to stop taking it.

What dose do I take? 

The usual dose of azithromycin is 250mg tablets (one capsule) three times per week; normally taken on a Monday, Wednesday, and Friday. In certain situations, your doctor may prescribe you a higher dose of 500mg. Occasionally, it may be prescribed for you to take every day. 

Take your dose 1 hour before food or at least 2 hours after food. Swallow whole with a glass of water.

What if I forget to take my dose? 

This should not cause any problems. Take your next dose at the normal time.

Will azithromycin interfere with any other medicines that I am taking? 

  • Azithromycin can interfere with many other medicines and herbal remedies. 
  • Tell your doctor or pharmacist if you are taking any other medicines or herbal remedies before you start taking azithromycin. 
  • Tell your doctor or pharmacist before you star t on any new medicines or herbal remedies while on azithromycin. 
  • If you are prescribed another antibiotic, check with your doctor whether you should continue to take azithromycin.

What should I do if I have a flare-up of my lung condition? 

Although azithromycin is an antibiotic, you may still need to take other antibiotics for any chest infections or flare-ups of your lung condition. You may need to stop your azithromycin when starting a course of antibiotics and your team will advise you.

Can I drink alcohol when taking azithromycin? 

Yes, within the government guidance of no more than 14 units of alcohol per week. Azithromycin does not interact with alcohol. 

More information 

If you have any other questions, please speak to the doctor or nurse who prescribed you the azithromycin.

Date published: 31 May 2026 Review due: 31 May 2029 PI number: BFT003626

AAC access methods

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Access in AAC means the way a person makes their communication system work. Directly touching a screen with a finger is the easiest way to make a device work, but for people who are unable to do this there are different access methods that can be explored.

Direct touch access

AAC direct touch access device with finger touching screen

Direct touch access means using your finger to select icons on a touchscreen device, such as a smartphone or tablet. This is a common AAC access method because it is the easiest way to make a selection. 

To make touch access easier, the device accessibility settings can be used. For example, press and holding for a set time to select, ignoring accidental touches or making the text bigger. 

Some AAC users use a keyguard, which is a thick plastic cover with holes that sits on the screen. Keyguards can help guide your finger to the right place and make it easier to select what you want without errors.

Partner assisted scanning (PAS)

Partner-assisted scanning (also known as PAS) is a communication method that can be used where someone cannot easily point, touch or see their AAC. Instead, a communication partner helps by reading out or pointing to choices, one at a time, in order. When the communication partner gets to the right word or symbol, the person communicates “yes” using their own reliable signal. This might be a sound, a gesture, a blink, or any agreed‑upon response.

Partner‑assisted scanning can be flexible and personalised. It allows the person to take part in conversations even if they cannot use a device directly. The partner works at the person’s pace, giving plenty of time for them to respond.

To see partner-assisted scanning using an alphabet board, watch this video

To see partner-assisted scanning using a communication book, watch this video

Pointer control

AAC pointer devices

Pointer control works like a computer mouse, where the cursor freely moves across the screen of a communication device using tools such as:

  • joystick
  • trackball 
  • mouse
  • trackpad
  • head mouse (allows you to control the cursor by moving your head)

This access method allows AAC users to navigate a communication aid without needing to touch the screen directly. Pointer control tools come in a range of size, shapes and sensitivities, to suit different needs. 

Eye pointing

Eye pointing is a communication method where an AAC user uses their eyes to look at objects, pictures, symbols, phrases or letters. Eye pointing can be used for everything from making simple choices, to complex systems that allow someone to generate full sentences. Some examples of eye pointing systems include:

  • E-Tran frame
  • MegaBee
  • Eye-Link 

To see someone using an E-Tran frame, watch this video

To someone using a MegaBee, watch this video

Eye gaze

Eye gaze access allows an AAC user to control a device’s cursor using only their eye movements. To do this the eyegaze camera directs an infared light into the AAC user’s eyes. This light is reflected back to the camera, allowing it to calculate exactly where the person is looking at the screen. Choosing an item to select on the screen can be done by waiting (dwelling), blinking or touching a switch.

Different eye gaze cameras suit different people so it can be useful to try a few different options. For some people, eye gaze may not be the most consistently reliable access method, and in these cases an alternative access method may need to be explored. 

To see how eye gaze technology works, watch this video

Switch access

A switch is something you press, touch or move near to make an electronic device do something. For example, to turn on a light, control your TV or to access a communication aid. There are many different kinds of switches. They work in different ways, need different amounts of pressure and can be used by different parts of the body. The photo below shows a small selection of switches and examples of how people might use them. 

AAC device switches

Photo description: 

  1. Ping-pong switch: Only requires light action. Is water and moisture resistant. Ideal for use as a head switch. 
  2. Buddy button with softy top – Durable and highly responsive switch. Gives auditory and tactile feedback with a click on activation. Using a softy top can reduce discomfort and improves tactile feedback.
  3. Wobble switch – Sprung switch that activates with light touch in any direction. 
  4. Finger mouse – Handheld mouse that can be used as a switch. Also used as a pointer for computer access. 
  5. FingerButton switch – Highly responsive with small activation area and very little force required to activate. Can be wraped around a finger.
  6. Pal pad switch – Ultra-sensitive and low-profile. Is durable and rigid. 
  7. Puff switch – Can be used hands-free. Use a puff (breath) to activate. 
  8. Pillow switch – Soft and smooth suitable for head or cheek activation.

To use a switch with a communication aid the switch can be used to move the highlight around the screen and then select what you want. To see how this works watch the video below. 

Weight Assessment and Management Service (WAMS)

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WAMS is a specialist service supporting people living with obesity who are motivated to explore behavioural, medical and/or surgical management of their weight.

We are a friendly team offering support and guidance to help you lose weight and improve your health and wellbeing. 

The team includes consultant endocrinologists (medical doctors), dietitians, psychologists, a pharmacist, and office staff. 

How does the service work?

WAMS is a 12 month service where you will be offered an assessment appointment followed by a support plan. This will be tailored to you. 
As you progress through the service, the team will discuss your care to find the best way to continue supporting you.

Our approach

We hope that you feel respected and valued during your time in our service. We are not here to shame or blame. Our approach is to view obesity as a complex, long-term health condition. 

Please be reassured that we would like to hear about what is actually happening in your life, rather than what you think we might want to hear. We are here to listen and help you to achieve the most positive outcomes that you can, and this is only really possible if you feel able to be open and honest about your situation.

What can you expect at your initial assessment?

At your first appointment you will speak with a consultant endocrinologist who will check for any medical causes for obesity and check other medical problems that may need treatment. You may be referred for further tests if considered necessary. These may include: blood tests, CT scans, camera investigations (endoscope). 

You will speak to a dietitian to understand your eating habits and explore your relationship with food, both now as well as in the past. We understand this can be difficult, but we encourage you to share what you can so that we can help you as best as possible. 

You may also see a psychologist who will ask about your wellbeing and help you to identify how your thoughts and feelings may be affecting your weight. They might make some suggestions to help you with your mood and work towards making changes.

What can you expect after your initial assessment?

After these first meetings, we will agree on a weight management plan for you. Sometimes we will need to signpost people onto other services before we can offer support. This is so that they are ready and able to work on their goals with our team. 

Most of our interventions are offered in an online group format, for example:

The Mood and Food programme

A blend of nutrition advice and support with the psychological aspects of eating – jointly run by dietitians and psychologists.

Our Coping with Emotion programme

A space in which to develop coping strategies for emotional eating behaviours – run by the psychology team.

Quotes from people who have attended sessions:

  • “The group sessions I have attended have been excellent and very informative.”
  • “Positive environment, non-judgemental, non-prescriptive. Lots of really useful advice and tips.”

There is the possibility of 1-1 sessions if the team feel that there are strong reasons for this. These may be online, via the phone, or in-person, depending on the situation.

Medical management of weight

Some people may be able to have medication to support weight loss. When available, this will be prescribed in line with local and National Institute for Health and Care Excellence (NICE) guidelines. 

People who are being prescribed medication for weight management by our team are able to receive this support for up to two years. 

Bariatric surgery (‘weight loss surgery’)

We work closely with members of the bariatric surgery service which is made up of surgeons, dietitians, psychologists and a nurse specialist.
Some people in the weight management service are interested in bariatric surgery, others are not, and some people are unable to have it for various reasons. 

It is normal for people to need support and preparation to make sure that they are ready for surgery. Our aim is to prepare people for the significant dietary and psychological changes which are required for surgery to be effective and safe.
Please note that completing your weight management plan in the WAMS service does not necessarily guarantee that you would be eligible for bariatric surgery. 

It is our policy that people who miss appointments without giving any notice, or cancel more than two consecutive appointments, may be discharged back to the care of their GP.

© North Bristol NHS Trust. This edition published May 2026. Review due May 2029. NBT002960.

Test Information

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This is a searchable database of information about tests offered by Severn Pathology. You can browse the index, enter a test name, part of a test name, abbreviation or clinical indication below.

Information available depends on the type of assay and department, but generally consists of alternative names, clinical indications, patient preparation (where appropriate), special precautions, department responsible for the test and reference ranges (where applicable).

The containers listed refer to those used to collect samples from adults locally in GP practices and hospital wards/outpatients. Details of the containers used for neonates, children and in the emergency zone (ED, AAU, ITU) can be found here Tube Guide and Recommended Order of Draw.

You may also find Lab Tests Online UK useful an additional resource for help you understand the many clinical laboratory tests that are used in diagnosis, monitoring and treatment of disease.

View
Special notes Tube type Sample type Test name Ideal volume Turnaround time Discipline
Special Precautions – Please click Test Name for further details 24 Serum 1,25-Dihydroxy Vitamin D 5 mL 4 weeks Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum 11-deoxycortisol 1 mL 1 week Clinical Biochemistry
Special Precautions – Please click Test Name for further details 20 Plasma 17 OHP 5 mL 14 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 31 Blood spot 17 OHP see notes 14 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 17 Plasma (fluoride oxalate) 3-Hydroxybutyrate 5 mL 7 days Clinical Biochemistry
24 Serum 5-Alpha Dihydrotestosterone 1 mL 28 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 5 Urine - 24 hour 5-HIAA n/a 7 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 20 Plasma 7-dehydrocholesterol 2 mL 28 days Clinical Biochemistry
24 Serum ACE 5 mL 7 days Clinical Biochemistry
34 CSF ACE 500 uL 6 weeks Clinical Biochemistry
24 Serum Acetylcholine Receptor Antibody 2 mL 3 weeks Immunology
Special Precautions – Please click Test Name for further details 24 Serum Aciclovir/CMMG <3 days Antimicrobial Reference Laboratory
Special Precautions – Please click Test Name for further details 14 Plasma ACTH 5 mL 5 days Clinical Biochemistry
24 Serum Active B12/HoloTC 1 mL 7 days Clinical Biochemistry
20 Plasma Acylcarnitines 2 mL 21 days Clinical Biochemistry
9 Blood spot Acylcarnitines 1x Spot 21 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 13 Plasma ADAMTS13 Urgent requests: 24 hours; Routine requests: 2 weeks. Haematology
Special Precautions – Please click Test Name for further details 34 Fluid Adenosine Deaminase in TB 1 mL 14 days Clinical Biochemistry
34 Bronchoalveolar lavage (BALs) and Sputums Adenovirus
Molecular assay (NAAT)
0.5 2 days Virology
34 Nasopharayngeal aspirates (NPAs) Adenovirus
Molecular assay (NAAT)
0.5 2 days Virology
43 Swabs (nose and throat) Adenovirus
Molecular assay (NAAT)
0.5 2 days Virology
11 Faecal sample Adenovirus
PCR
pea sized amount 2 days Microbiology
43 Swab (eye) Adenovirus (qualitative)
PCR (In house)
0.5 4 days Virology
14 EDTA Blood sample Adenovirus (quantitative)
PCR (In house)
0.45 3 days Virology
24 Serum Adrenal Cortex Antibody 2 mL 14 working days Immunology
34 CSF AFP 2 mL 3 days Clinical Biochemistry
24 Serum AFP 5 mL 1 day Clinical Biochemistry
24 Serum Albumin 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
24 Fluid Albumin 5 mL 3 days Clinical Biochemistry
35 Urine - Random Albumin / creatinine ratio n/a 1 day Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Plasma Aldosterone 5 mL 21 days Clinical Biochemistry
24 Serum Alk Phos Isoenzymes 5 mL 7 days Immunology
24 Serum Allergen specific IgE 2 mL 7 working days Immunology
24 Serum ALP 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
24 Serum Alpha 1 antitrypsin activity 5 mL 3 days Immunology
24 Serum Alpha 1 antitrypsin phenotype 5 mL 14 working days Immunology
24 Serum Alpha subunit 2 mL 5 weeks Clinical Biochemistry
24 Serum ALT 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 10 Whole Blood Aluminium 5 mL 7 days Clinical Biochemistry
24 Serum AMH 2 mL 1 week Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Amikacin <1 day Antimicrobial Reference Laboratory
Special Precautions – Please click Test Name for further details 34 CSF Amino Acids CSF 1 mL 14 days Clinical Biochemistry
20 Plasma Amino Acids Plasma 2 mL 21 days Clinical Biochemistry
35 Urine - Random Amino Acids Urine 5 mL 21 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Plasma Amiodarone 5 mL 7 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Plasma Ammonia 1 mL 2 hours Clinical Biochemistry
24 Fluid Amylase 5 mL 3 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 35 Urine - Random Amylase 5 mL 4 hours Clinical Biochemistry
24 Serum ANCA 2 mL 4 working days Immunology
24 Serum Androstenedione 5 mL 28 days Clinical Biochemistry
24 Serum Anion Gap 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
16 Whole Blood Antenatal Blood Group and Antibody Screen 4 mL 1 day Blood Transfusion
24 Clotted blood sample Antenatal Screen - HBsAg, HIV and Syphilis Serology 0.5 3 days Virology
24 Serum Anti Cardiolipin Antibody 2ml 1 week Immunology
24 Serum Anti PLA2 R 2ml 2 weeks Immunology
13 Whole Blood Anti Thrombin 3 full tubes 21 days Haematology
13 Plasma Anti-Xa 2.7 mL 4 hours for UFH, 24 hours for all other tests. If result is required more urgently than 24 hours, please contact haematology laboratory and testing will be expedited if possible. Haematology
Special Precautions – Please click Test Name for further details 16 Whole Blood ANTIBODY Investigation (red cells) 6ml x 2 Up to 72 hours Blood Transfusion
35 Urine Antihypertensive Drug Assay 5mL random 2 weeks Clinical Biochemistry
24 Serum Antinuclear Antibody 2 mL 4 working days Immunology
Special Precautions – Please click Test Name for further details 14 Whole Blood Apo E genotyping 4 mL 28 days Genetics
24 Serum Apolipoprotein B 1 mL 1 week Clinical Biochemistry
13 Whole Blood APTT/APTT-R 2.7 mL 24 hours Haematology
Special Precautions – Please click Test Name for further details 14 Whole blood Arsenic 2 mL 2 weeks Clinical Biochemistry
Special Precautions – Please click Test Name for further details 34 Urine Arsenic (urine) 5 mL 2 weeks Clinical Biochemistry
Special Precautions – Please click Test Name for further details 25 Fluid Asialotransferrin see notes 3 working days Immunology
34 Broncheolar lavage (BAL) samples Aspergillus Antigen 700µL Mean 1 day Mycology Reference Laboratory
24 Clotted blood samples Aspergillus Antigen 700µL Mean 1 day Mycology Reference Laboratory
24 serum Aspergillus IgG 2ml 1 week Immunology
34 Fluids - e.g. CSF, vitreous Aspergillus PCR 100µL (Minimum) Mean 3 days Mycology Reference Laboratory
34 Tissue - e.g. lung biopsy, corneal scraping Aspergillus PCR 100µL (Minimum) Mean 3 days Mycology Reference Laboratory
24 Clotted blood samples Aspergillus PCR 200µL (Minimum) Mean 3 days Mycology Reference Laboratory
34 Bronchoalveolar lavage (BALs) Aspergillus PCR 100µL (Minimum) Mean 3 days Mycology Reference Laboratory
24 Clotted blood samples Aspergillus Precipitins 200µL Mean 3 days Mycology Reference Laboratory
Special Precautions – Please click Test Name for further details 24 Serum AST 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
11 Faecal sample Astrovirus
PCR
pea sized amount 2 days Microbiology
24 Serum Autoimmune Liver Disease Antibodies 2 mL 4 working days Immunology
43 Swabs (nose and throat) Avian Influenza A PCR
Molecular assay (NAAT)
0.5 2 days Virology
24 Serum Avian proteins IgG 2ml 1 week Immunology
34 BAL MCS BAL MCS 3 mL 12 days Microbiology
Special Precautions – Please click Test Name for further details 35 Urine - Random Barbiturates 5 mL 3 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Benzylpenicillin (Penicillin G) <3 days Antimicrobial Reference Laboratory
24 Serum Beta 2 Glycoprotein 1 2 mL 7 working days Immunology
24 Serum Beta 2 microglobulin 2 mL 7 working days Immunology
24 Clotted blood samples Beta D Glucan 200µL Mean <1 day Mycology Reference Laboratory
24 Serum Bicarbonate 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
24 Serum Bilirubin 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details Plasma Bilirubin - infants 1 full paediatric lithium heparin tube 4 hours Clinical Biochemistry
24 Serum Bilirubin-(Conjugated fraction) 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 9 Blood spot Biopterins 6x Spots 28 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Plasma Biotinidase 1 mL 7 days Clinical Biochemistry
14 EDTA Blood sample BK virus (quantitative)
PCR (In house)
0.45 3 days Virology
34 Urine BK virus (quantitative)
PCR (In house)
0.5 3 days Virology
Special Precautions – Please click Test Name for further details 14 Whole Blood Blood Film 24 hours Haematology
Special Precautions – Please click Test Name for further details 18 Whole Blood Blood Gases see notes n/a Clinical Biochemistry
Special Precautions – Please click Test Name for further details Bone Marrow Bone Marrow Aspirate or Trephine Haematology
24 Serum Bone profile 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
43 Pernasal swabs Bordetella parapertussis
Molecular assay (NAAT)
0.5 3 days Virology
43 Pernasal swabs Bordetella pertussis
Molecular assay (NAAT)
0.5 3 days Virology
24 Clotted blood sample Bordetella pertussis antibodies
IgG
0.17 5 days Virology
24 Clotted blood sample Borrelia burgdorferi (Lyme) antibodies
IgG and IgM
0.38 4 days Virology
Special Precautions – Please click Test Name for further details 28 Urine - Random C-peptide : creatinine ratio 2 mL 1 week Clinical Biochemistry
14 Plasma C-Peptide (plasma) 5ml 1 week Clinical Biochemistry
11 Faeces C.difficile toxin Pot should be at least 1/3 full 24 hours Microbiology
Special Precautions – Please click Test Name for further details 24 Serum C1 Esterase Inhibitor 2 mL 14 working days Immunology
Special Precautions – Please click Test Name for further details 14 Whole Blood C3 Degradation Products 3 mL 5 working days Immunology
24 Serum C3 Nephritic Factor 2 mL 7 working days Immunology
24 Serum CA 125 5 mL 1 day Clinical Biochemistry
24 Serum CA 15-3 5 mL 1 day Clinical Biochemistry
24 Serum CA 19-9 5 mL 1 day Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Whole Blood Cadmium 4 mL 14 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 35 Urine - Random Cadmium 5 mL 14 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Caeruloplasmin 5 mL 4 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Calcitonin 5 mL 14 days Clinical Biochemistry
4 Urine - 24 hour Calcium n/a 3 days Clinical Biochemistry
24 Serum Calcium 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 27 Serum and Urine Calcium excretion index 5 mL 3 days Clinical Biochemistry
11 Faeces Calprotectin 5 g 7 working days Immunology
24 Clotted blood samples Candida Precipitins 200µL Mean 3 days Mycology Reference Laboratory
24 Clotted blood samples Candida Antigen 300µL Mean 1.6 days Mycology Reference Laboratory
34 Fluids - e.g. CSF, vitreous Candida PCR 100µL (Minimum) Mean 3 days Mycology Reference Laboratory
34 Tissue - e.g. lung biopsy, corneal scraping Candida PCR 100µL (Minimum) Mean 3 days Mycology Reference Laboratory
24 Clotted blood samples Candida PCR 200µL (Minimum) Mean 3 days Mycology Reference Laboratory
35 Urine - Random Cannabinoids 5 mL 3 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Carbamazepine 5 mL 1 day Clinical Biochemistry
Special Precautions – Please click Test Name for further details 18 Whole Blood Carboxyhaemoglobin full tube n/a Clinical Biochemistry
24 Serum Cardiac Muscle Antibody 2 mL 21 working days Immunology
Special Precautions – Please click Test Name for further details 35 Urine - Random Carnitine, 5 mL 14 days Clinical Biochemistry
Urine - 24 hour Catecholamines
14 Whole Blood CD 4 Counts 3 mL 1 working day Immunology
Special Precautions – Please click Test Name for further details 24 Serum CDT 5 mL 14 days Clinical Biochemistry
24 Serum CEA 5 mL 4 days (due to batching of the assay) Clinical Biochemistry
24 Serum Centromere Antibody 2 mL 7 working days Immunology
1 Aptima Swab Chlamydia trachomatis
NAAT
1 tube 3 days Virology
38 Aptima Urine Chlamydia trachomatis
NAAT
1 tube 3 days Virology
24 Clotted blood sample Chlamydia trachomatis antibodies
IgG
0.17 4 days Virology
1 Swab (eye) Chlamydia trachomatis/Neisseria gonorrhoeae
NAAT
1 tube 3 days Virology
37 See Notes Chlamydia/ GC other swabs n/a 10 days Microbiology
38 Urine - Random Chlamydia/ GC urine n/a 10 days Microbiology
1 See Notes Chlamydia/ GC vaginal swabs n/a 10 days Microbiology
Special Precautions – Please click Test Name for further details 24 Serum Chloramphenicol <3 days Antimicrobial Reference Laboratory
24 Serum Chloride 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
20 Plasma Cholestanol 1 mL 21 days Clinical Biochemistry
24 Serum Cholesterol 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
24 Fluid Cholesterol 2 mL 3 days Clinical Biochemistry
14 Whole Blood Cholinesterase Genotype 4 mL 10 - 12 weeks Clinical Biochemistry
14 EDTA (whole blood) Cholinesterase Studies 5 mL 3 - 4 weeks Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Whole Blood Chromium 4 mL 14 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Plasma Chromogranin A 5 mL 21 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Ciprofloxacin <3 days Antimicrobial Reference Laboratory
Special Precautions – Please click Test Name for further details 4 Urine - 24 hour Citrate n/a 7 days Clinical Biochemistry
20 Plasma Citrulline 1 mL Clinical Biochemistry
24 Serum CK 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
13 Whole Blood Clauss Fibrinogen 2.7 mL 24 hours Haematology
13 Whole Blood Clotting Screen 2.7 mL 24 hours Haematology
14 Plasma Clozapine Level 2.7 mL 10 days
34 Urine CMV
PCR (In house)
0.5 3 days Virology
24 Clotted blood sample CMV IgG CMV IgG and IgM 0.190, CMV IgG 0.17 4 days Virology
24 Clotted blood sample CMV IgM CMV IgG and IgM 0.19, CMV IgM 0.17 4 days Virology
Special Precautions – Please click Test Name for further details 14 Whole Blood Cobalt 4 mL 14 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Colistin <3 days
Antimicrobial Reference Laboratory
24 Serum Complement C3 + C4 2 mL 4 working days Immunology
Special Precautions – Please click Test Name for further details 24 Serum Complement Function 5 mL 14 Working Days Immunology
Special Precautions – Please click Test Name for further details 24 Serum Copeptin 5 mL 14 days Clinical Biochemistry
24 Serum Copper 5 mL 7 days Clinical Biochemistry
5 Urine - 24 hour Copper n/a 7 days Clinical Biochemistry
24 Serum Cortisol 5 mL 1 day Clinical Biochemistry
34 Bronchoalveolar lavage (BALs) and Sputums COVID-19
Molecular assay (NAAT)
0.5 1 day Virology
43 Swabs (nose and throat) COVID-19
Molecular assay (NAAT)
0.5 1 day Virology
34 Nasopharayngeal aspirates (NPAs) COVID-19
Molecular assay (NAAT)
0.5 1 day Virology
20 Plasma Creatine Studies 2 mL 21 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 35 Urine - Random Creatine Studies 5 mL 14 days Clinical Biochemistry
34 Dialysate Creatinine 2 mL 1 day Clinical Biochemistry
24 Fluid Creatinine 2 mL 3 days Clinical Biochemistry
24 Serum Creatinine 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 26 Serum and Urine Creatinine clearance n/a 8 hours Clinical Biochemistry
24 Serum Crithidia for dsDNA antibodies 2ml 14 working days Immunology
Special Precautions – Please click Test Name for further details 0 Whole Blood Crossmatch - (Lymphocyte) for Renal Transplantation Immunology see "sample required" Live donor typing and crossmatch = 28 working days Immunology
Special Precautions – Please click Test Name for further details 16 Whole Blood Crossmatch - Blood Transfusion 4 mL See Notes Blood Transfusion
24 Serum CRP 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Cryoglobulin Discuss with Laboratory 10 working days Immunology
24 Clotted blood samples Cryptococcus neoformans antigens 500µL Mean 3 days Mycology Reference Laboratory
34 CSF Cryptococcus neoformans antigens 500µL Mean 3 days Mycology Reference Laboratory
Special Precautions – Please click Test Name for further details CSF CSF neurodegenerative markers 0.5mL in each tube 10 working days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Plasma CTx 2 mL 21 days Clinical Biochemistry
24 Serum Cyclic Citrullinated Peptide Antibodies 2 mL 14 Working days Immunology
Special Precautions – Please click Test Name for further details 24 Serum Cycloserine <3 days Antimicrobial Reference Laboratory
Special Precautions – Please click Test Name for further details 14 Whole Blood Cyclosporin 4 mL 3 days Clinical Biochemistry
24 Serum Cystatin C 2mL 7 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 4 Urine - 24 hour Cystine 24 hour excretion n/a 21 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 33 Urine - timed Cystine day/night n/a 21 days Clinical Biochemistry
35 Urine - Random Cystine Random Urine 5 mL 21 days Clinical Biochemistry
34 Amniotic fluid Cytomegalovirus CMV (quantitative)
PCR (In house)
0.2 3 days Virology
34 CSF Cytomegalovirus CMV (quantitative)
PCR (In house)
0.2 3 days Virology
14 EDTA Blood sample Cytomegalovirus CMV (quantitative)
PCR (In house)
0.45 3 days Virology
34 Nasopharayngeal aspirates (NPAs) Cytomegalovirus CMV(qualitative)
PCR (In house)
0.5 3 days Virology
24 Clotted blood sample Cytomegalovirus IgG avidity 0.17 4 days Virology
34 Bronchoalveolar lavage (BALs) and Sputums Cytomegaloviurs CMV (qualitative)
PCR (In house)
0.5 3 days Virology
13 Whole Blood D-Dimer 2.7 mL 24 hours Haematology
Special Precautions – Please click Test Name for further details 24 Serum Daptomycin <3 days Antimicrobial Reference Laboratory
14 Whole Blood DAT 3 mL 24 hours Blood Transfusion
Special Precautions – Please click Test Name for further details 24 Serum DHEAS 5 mL 10 days Clinical Biochemistry
24 Serum Diabetes Autoantibodies (ZnT8, GAD, IA2) 2 mL 28 working days Immunology
Special Precautions – Please click Test Name for further details 24 Serum Digoxin 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
24 Serum Down's Syndrome Screening 5 mL 7 days Clinical Biochemistry
14 Whole Blood DQ6(DQB1*06:02) 3 mL 14 working days Immunology
Special Precautions – Please click Test Name for further details 35 Urine - Random Drug (Overdose) Screen 5 mL 3 days Clinical Biochemistry
35 Urine - Random Drugs of Abuse 5 mL 4 days Clinical Biochemistry
24 Serum ds-DNA antibodies 2 mL 7 working days Immunology
14 EDTA Blood sample EBV (quantitative)
PCR (In house)
0.45 3 days Virology
24 Serum eGFR 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
24 Fluid Electrolytes 2 mL 3 days Clinical Biochemistry
24 Serum ELF 5 mL 10 days Clinical Biochemistry
24 Serum Endomysium Antibody 2 mL Immunology
43 Vesicle swab Enterovirus
PCR (In house)
0.5 4 days Virology
34 Vesicle fluid Enterovirus
PCR (In house)
0.5 3 days Virology
43 Vesicle Swab Enterovirus
PCR (In house)
0.5 4 days Virology
34 CSF Enterovirus
PCR (In house)
0.2 3 days Virology
14 EDTA Blood sample Enterovirus
PCR (In house)
0.45 3 days Virology
43 Swabs Throat swab Enterovirus
PCR (In house)
0.5 3 days Virology
11 Faecal sample Enterovirus
PCR (In house)
pea sized amount 3 days Virology
24 Whole Blood EPO 5 mL 10 days Clinical Biochemistry
24 Clotted blood sample Epstein Barr Virus (EBV) IgG 0.17 4 days Virology
24 Clotted blood sample Epstein Barr Virus (EBV) serology
EBNA VCA IgG and IgM
0.42 4 days Virology
34 CSF Epstein Barr Virus EBV (qualitative)
PCR (In house)
0.2 3 days Virology
Special Precautions – Please click Test Name for further details 24 Serum Ethambutol <3 days
Antimicrobial Reference Laboratory
35 Urine - Random Ethanol 2 mL 1 day Clinical Biochemistry
Special Precautions – Please click Test Name for further details 17 Plasma Ethanol 5 mL 4 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 17 Plasma Ethylene glycol 5 mL 1 day Clinical Biochemistry
24 Serum Extractable Nuclear Antigen 2 mL 7 working days Immunology
Special Precautions – Please click Test Name for further details 14 Whole Blood Fabry Screen 4 mL 2-3 weeks Clinical Biochemistry
13 Plasma Factor II 2 full tubes 2 weeks Haematology
13 Whole Blood Factor IX Assay 2.7 mL 10 days Haematology
13 Plasma Factor V 2 full tubes 2 weeks Haematology
13 Whole Blood Factor V Leiden 2.7 mL 1 month Haematology
13 Plasma Factor VII 2 full tubes 2 weeks Haematology
13 Whole Blood Factor VIII Assay 2.7 mL 10 days Haematology
Special Precautions – Please click Test Name for further details 13 Plasma Factor VIII Inhibitor 2 full tubes 2 weeks, urgents will be processed as required following discussion with Haematologist Haematology
13 Plasma Factor X 2 full tubes 10 days Haematology
13 Plasma Factor XI 2 full tubes 10 days Haematology
13 Plasma Factor XII 2 full tubes 10 days Haematology
13 Plasma Factor XIII 2 full tubes 10 days Haematology
11 Faeces Faecal Elastase 5 g 16 working days Immunology
Faecal reducing substances
Fat Globules
24 Serum Ferritin 5 mL 24 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Plasma FGF-23 2 mL 4 weeks Clinical Biochemistry
24 Plasma AND Serum FIB-4 5 mL 24 hours Clinical Biochemistry
Faecal FIT 2 working days Immunology
Special Precautions – Please click Test Name for further details 24 Serum Flucloxacillin <3 days Antimicrobial Reference Laboratory
Special Precautions – Please click Test Name for further details Serum Fluconazole < 2 days Antimicrobial Reference Laboratory
Special Precautions – Please click Test Name for further details Serum Flucytosine < 2 days Antimicrobial Reference Laboratory
Special Precautions – Please click Test Name for further details 16 Whole Blood Foetal leak investigation 4 mL 1 day Blood Transfusion
24 Serum Folate 5 mL 24 hours Clinical Biochemistry
24 Serum Free androgen index 5 mL 7 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 17 Plasma (fluoride oxalate) Free Fatty Acids 2 mL 7 days Clinical Biochemistry
16 Whole Blood Free fetal DNA for fetal Rh typing 4 mL 15 days Blood Transfusion
Special Precautions – Please click Test Name for further details 24 Serum Free Light Chains 2 mL 7 working days Immunology
Special Precautions – Please click Test Name for further details 24 Serum Free Testosterone 5 mL 7 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Fructosamine 5 mL 7 days Clinical Biochemistry
24 Serum FSH 5 mL 1 day Clinical Biochemistry
14 Whole Blood Full Blood Count 4 mL 24 hours Haematology
35 Urine - Random Galactitol 5 mL 28 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 20 Whole Blood Galactokinase 1 mL 14 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 20 Whole Blood Galactosaemia screen 1 mL 7 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 20 Whole Blood Galactose-1-phosphate 0.5 mL 28 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 20 Whole Blood Galactose-1-phosphate uridyl transferase (quantitative) 1 mL 28 days Clinical Biochemistry
24 Serum Gamma GT 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Ganciclovir <3 days Antimicrobial Reference Laboratory
24 Serum Ganglioside Antibodies 2 mL 21 working days Immunology
24 Serum Gastric Parietal Cell Antibody 2 mL 4 working days Immunology
Special Precautions – Please click Test Name for further details 14 Plasma Gastrin 5 mL 28 days Clinical Biochemistry
24 Serum GBM Antibody 2 mL 7 working days Immunology
Special Precautions – Please click Test Name for further details 24 Serum Gentamicin 5mL Hospital patients 4 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Plasma Glucagon 5 mL 28 days Clinical Biochemistry
17 CSF Glucose 2 mL 4 hours Clinical Biochemistry
17 Fluid Glucose 2 mL 3 days Clinical Biochemistry
24 Serum Glucose (inpatients only) 5 mL 4 hours Clinical Biochemistry
17 Plasma Glucose (outpatients/General practice) 2 mL 1 day Clinical Biochemistry
14 Whole Blood Glucose 6 Phosphate Dehydrogenase 4 mL 5 working days, 10 working days if sent to referral laboratory for quantitative testing Haematology
17 Plasma Glucose tolerance test 2 mL 8 hours Clinical Biochemistry
17 Plasma Glucose tolerance test in Pregnancy 2 mL 1 day Clinical Biochemistry
16 Whole Blood Group and Hold 4 mL 24 hours Blood Transfusion
Special Precautions – Please click Test Name for further details 24 Serum Growth Hormone 5 mL 7 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Plasma Gut Hormones 10 mL 28 days Clinical Biochemistry
11 Faeces H.pylori 1/3 full/10ml minimum 3 days Microbiology
14 Whole Blood Haematocrit 4 mL 24 hours Haematology
14 Whole Blood Haemoglobin 4 mL 24 hours Haematology
14 Whole Blood Haemoglobinopathy screen 4 mL 3 days Haematology
24 Serum Haemophilus B Antibodies (HIB) 2 mL 14 days Immunology
34 Urine - Random and Bone Marrow Haemosiderin 2 mL 7 days Haematology
24 Serum Haptoglobin 5 mL 7 working days Clinical Biochemistry
14 Whole Blood HbA1c 4 mL 3 working days Haematology
34 CSF hCG 2 mL 3 days Clinical Biochemistry
24 Serum hCG 5 mL 1 day (2 hours for urgent requests) Clinical Biochemistry
See Notes hCG (Molar) Clinical Biochemistry
24 Serum HDL Cholesterol 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
24 Clotted blood sample Hepatitis A
IgM and IgG
Anti-HAV 0.24 HAVIgM 0.17 3 days Virology
14 EDTA Blood sample Hepatitis B (quantitative)
Molecular assay
1mL 5 days Virology
24 Clotted blood sample Hepatitis B Surface Antibody Anti-HBs (Quantitative) 0.3 3 days Virology
24 Clotted blood sample Hepatitis B Surface Antigen (HBsAG) 0.5 3 days - Screen 7 days - Confirmations Virology
14 EDTA Blood sample Hepatitis C (genotype)
PCR (In house)
0.2 14 days Virology
14 EDTA Blood sample Hepatitis C (quantitative)
PCR (In house)
1mL 5 days Virology
24 Clotted blood sample Hepatitis C antibody
Total antibody screening & confirmation testing
0.5 3 days - Screen 7 days - Confirmations Virology
24 Clotted blood sample Hepatitis E
IgM & IgG
0.5 4 days Virology
24 Clotted blood sample Hepatits B core antibody 0.26 3 days Virology
43 Swab (eye) Herpes simplex HSV 1 and 2
PCR (In house)
0.5 4 days Virology
34 CSF Herpes Simplex HSV 1 and 2
PCR (In house)
0.2 3 days Virology
43 Vesicle Swab Herpes simplex HSV 1 and 2
PCR (In house)
0.5 4 days Virology
24 Clotted blood samples Herpes Simplex HSV 1 and 2 specific serology
IgG
0.19 4 days Virology
14 EDTA blood sample Herpes Simplex HSV 1and 2
PCR (In house)
0.45 3 days Virology
14 EDTA (whole blood) HGA - HFE Gene Analysis 1-5 ml Genetics (Exeter lab)
14 EDTA Blood sample HHV6 - Blood
PCR (In house)
0.45 3 days Virology
34 CSF HHV6 - CSF
PCR
0.45 3 days Virology
24 Serum Histone antibodies 2 mL 21 working days Immunology
Special Precautions – Please click Test Name for further details 24 Serum HIT 1 day for urgent requests, otherwise 5 days. Haematology
14 EDTA Blood sample HIV (quantitative)
Molecular assay
1mL 7 days Virology
24 Clotted blood sample HIV 1 and 2 antigen/antibody
Confirmation
0.5 7 days - Confirmations Virology
24 Clotted blood sample HIV 1 and 2 antigen/antibody
Total antibody/antigen
0.35 3 days - Screen 4 days - confirmations Virology
24 Serum HLA antibody screen 8 mL 14 working days Immunology
15 Whole Blood HLA type (DR,DQ,DP)Class II 8 mL 28 working days Immunology
15 Whole Blood HLA type(A,B,C)Class I 8 mL 28 working days Immunology
14 Whole Blood HLA-A29 3 mL 14 working days Immunology
14 Whole Blood HLA-B27 3 mL 14 working days Immunology
14 Whole Blood HLA-B51(5) 3 mL 14 working days Immunology
14 Whole Blood HLA-B57(B*57:01) 3 mL 10 working days Immunology
14 Whole Blood HLA-DQ2+DQ8(3) 3 mL 14 working days Immunology
Special Precautions – Please click Test Name for further details 14 Plasma Homocysteine (Total) 2 mL 7 days Clinical Biochemistry
24 Clotted blood sample HTLV antibody
Total Antibody screening
0.25 3 days Virology
34 Bronchoalveolar lavage (BALs) and Sputums Human metapneumovirus
Molecular assay (NAAT)
0.5 2 days Virology
43 Swabs (nose and throat) Human metapneumovirus
Molecular assay (NAAT)
0.5 2 days Virology
34 Nasopharayngeal aspirates (NPAs) Human metapneumovirus
Molecular assay (NAAT)
0.5 2 days Virology
35 Urine - Random HVA 5 mL 7 days Clinical Biochemistry
24 Serum IgE 2 mL 7 working days Immunology
24 Serum IGF-1 5 mL 5 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum IGFBP-3 5 mL 14 days Clinical Biochemistry
24 Serum IgG Subclasses 2 mL 7 working days Immunology
14 Whole Blood Immunodeficiency (Immunophenotyping) 3 mL 2 working days Immunology
Special Precautions – Please click Test Name for further details n/a Immunodeficiency Investigations Immunology
24 Serum Immunoglobulins 2 mL 3 working days Immunology
7 Rectal Swab Infection screen – VRE 3 days Microbiology
7 Various Infection screen Carbapenemase screen (rectal swab) n/a 3 days Microbiology
Various Infection screen MRC MRC screen for ESBL-producing Enterobacterales n/a 3 days Microbiology
Various Infection screen MRSA Screen n/a 2days Microbiology
Various Infection screen MSSA Screening (Renal/ Spinal) n/a 3 days Microbiology
7 Various Infection screen Pseudomonas Screening (NICU) n/a 3 days Microbiology
14 Plasma Infectious Mononucleosis 3 mL 72 hours Haematology
34 Nasopharayngeal aspirates (NPAs) Influenza A Virus
Molecular assay (NAAT)
0.5 2 days Virology
43 Swabs (nose and throat) Influenza A Virus
Molecular assay (NAAT)
0.5 2 days Virology
34 Bronchoalveolar lavage (BALs) and Sputums Influenza A virus Molecular assay (NAAT) 0.5 2 days Virology
43 Swabs (nose and throat) Influenza B Virus
Molecular assay (NAAT)
0.5 2 days Virology
34 Nasopharayngeal aspirates (NPAs) Influenza B Virus
Molecular assay (NAAT)
0.5 2 days Virology
34 Bronchoalveolar lavage (BALs) and Sputums Influenza B virus
Molecular assay (NAAT)
0.5 2 days Virology
13 Whole Blood INR 2.7 mL 24 hours Haematology
Special Precautions – Please click Test Name for further details 44 Plasma Insulin (Paediatric) 1 mL 1 working day Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Insulin and C-peptide 5 mL 14 days Clinical Biochemistry
24 Serum Insulin Antibodies 2 mL 21 working days Immunology
24 Serum Intrinsic Factor Antibodies 5 mL 10 days Clinical Biochemistry
24 Serum Iohexol GFR 2ml 7 days Clinical Biochemistry
24 Serum Iron 5 mL <4 hours Clinical Biochemistry
24 Serum Iron and Transferrin Saturation 5 mL 1 day Clinical Biochemistry
Special Precautions – Please click Test Name for further details Serum Isavuconazole < 2 days Antimicrobial Reference Laboratory
17 Whole Blood Collected in Fluoride Oxalate (Fx) Tube Isoniazid (+ N-Acetyl-Isoniazid) 1-2 ml <3 days (from day of receipt) Antimicrobial Reference Laboratory
Special Precautions – Please click Test Name for further details n/a Issue of Albumin Solution n/a Blood Transfusion
Special Precautions – Please click Test Name for further details n/a Issue of Fresh Frozen Plasma n/a Blood Transfusion
Special Precautions – Please click Test Name for further details n/a Issue of Platelets n/a Blood Transfusion
Special Precautions – Please click Test Name for further details Serum Itraconazole < 2 days Antimicrobial Reference Laboratory
Special Precautions – Please click Test Name for further details 35 Urine - Random Ketones 5 mL n/a Clinical Biochemistry
17 CSF Lactate 2 mL 4 hours Clinical Biochemistry
17 Plasma Lactate (Laboratory analysis)   2 mL 4 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 18 Whole Blood Lactate (Point of Care Testing) n/a n/a Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Plasma Lamotrigine 5 mL 1 - 2 weeks Clinical Biochemistry
24 Fluid LDH 2 mL 3 days Clinical Biochemistry
24 Serum LDH 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
34 CSF LDH 0.5 mL 3 days Clinical Biochemistry
24 Serum LDL Cholesterol 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
35 Urine - Random Lead 5 mL 7 days Clinical Biochemistry
14 Whole Blood Lead 1 mL 7 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details Leflunomide
34 Urine Legionella antigen 1 day Microbiology
14 Bone Marrow Leukaemial/Lymphoma Immunophenotyping 0.5 mL 1 working day Immunology
Special Precautions – Please click Test Name for further details 34 Lymph Nodes Leukaemial/Lymphoma Immunophenotyping see notes 1 working day Immunology
Special Precautions – Please click Test Name for further details 34 Other fluids Leukaemial/Lymphoma Immunophenotyping see notes 1 working day Immunology
14 Whole Blood Leukaemial/Lymphoma Immunophenotyping 3 mL 1 working day Immunology
Special Precautions – Please click Test Name for further details 20 Whole Blood Leukocyte Cystine 4 mL 28 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Levofloxacin <3 days Antimicrobial Reference Laboratory
24 Serum LFT 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
24 Serum LH 5 mL 1 day Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Linezolid <3 days Antimicrobial Reference Laboratory
24 Serum Lipase 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
24 Serum Lipid Profile 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Lipoprotein (a) 5 mL 21 days Clinical Biochemistry
24 Serum Lipoprotein Electrophoresis 5 mL 14 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Lithium 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
24 Serum Liver Kidney Microsomal 2 mL 4 working days Immunology
24 Serum Liver line blot 2ml 2 weeks Immunology
Special Precautions – Please click Test Name for further details 13 Whole Blood Lupus Anticoagulant 3 full tubes 10 days Haematology
Special Precautions – Please click Test Name for further details 20 Whole Blood Lymphocyte Function Tests 7 mL 7 working days Immunology
Special Precautions – Please click Test Name for further details 24 Serum Macro CK 5 mL 4-6 weeks Clinical Biochemistry
24 Serum Macroprolactin 5 mL 14 days Clinical Biochemistry
24 Serum Macroprolactin confirmation 2 mL 3 weeks Clinical Biochemistry
4 Urine - 24 hour Magnesium n/a 3 days Clinical Biochemistry
24 Serum Magnesium 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Whole Blood Malaria Parasites 4 mL 24 hours, 7 working days if sent to Referral Laboratory for confirmation Haematology
Special Precautions – Please click Test Name for further details 10 Whole Blood Manganese 5 mL 14 days Clinical Biochemistry
24 Serum Mannose Binding Lectin 2 mL 14 working days Immunology
Special Precautions – Please click Test Name for further details 14 Whole Blood Manual Blood Film including White Cell differential 24 hours Haematology
Special Precautions – Please click Test Name for further details 24 Serum Mast Cell Tryptase 2 mL 9 working days Immunology
14 Whole Blood MCH 4 mL 24 hours Haematology
14 Whole Blood MCHC 4 mL 24 hours Haematology
8 Whole Blood MCS (Blood Culture) Adults: 8-10mL blood per blood culture bottle; Paeds: 1-3mL blood. Wherever possible, please ensure that each bottle of the blood culture set is inoculated with the correct volume of blood. Smaller volumes adversely affect the sensitivity of the assay. 6 days Microbiology
34 CSF MCS (Cerebrospinal fluid) 3 mL 4 hours Microscopy
4 days Culture & sensitivities
Microbiology
Corneal Scrapes MCS (Corneal Scrapes) 10 days Microbiology
7 Swab MCS (Ear / left / right) n/a 4 days Microbiology
7 Swab MCS (Eye / left / right) n/a 4 days Microbiology
Special Precautions – Please click Test Name for further details 11 Faeces MCS (Faeces) 1/3 full/10ml minimum 4 days Microbiology
34 Fluid MCS (Fluids) 3 mL 8 days Microbiology
7 Swab MCS (Genital Swabs) n/a 4 days Microbiology
7 Mouth MCS (Mouth Swab) n/a 4 days Microbiology
7 MCS (Nose swab) n/a 4 days Microbiology
41 Penile / Urethral MCS (Penile / Urethral swab) n/a 4 days Microbiology
34 Peritoneal fluid MCS (Peritoneal Dialysis fluid) n/a 8 days Microbiology
34 Pus MCS (Pus) n/a 10 days Microbiology
7 Swab MCS (Skin swab) n/a 4 days Microbiology
34 Sputum MCS (Sputum) n/a 5 days Microbiology
7 Swab MCS (Throat swab) n/a 4 days Microbiology
34 Tip MCS (Tip) n/a 4 days Microbiology
34 Tissue MCS (Tissues) n/a 10 days Microbiology
34 Trachael aspirate MCS (Tracheal aspirate) n/a 4 days Microbiology
28 Urine MCS (Urine Catheter) > 3 ml 3 days Microbiology
28 Urine MCS (Urine) > 3 ml 3 days Microbiology
7 Swab MCS (Wound Swab) n/a 4 days Microbiology
14 Whole Blood MCV 4 mL 24 hours Haematology
24 Clotted blood sample Measles IgG 0.17 4 days Virology
24 Clotted blood samples Measles IgG and IgM 0.19 4 days Virology
43 Swabs (nose and throat) Measles PCR
PCR (In house)
0.5 3 days Virology
35 Urine - Random Mercury 1 mL 14 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Whole Blood Mercury 1 mL 14 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Meropenem <3 days Antimicrobial Reference Laboratory
43 Swabs (nose and throat) MERS-CoV
Molecular assay (NAAT) Biofire Film array RP2
0.5 4 hours from receipt for initial screening. Virology
Special Precautions – Please click Test Name for further details 24 Serum Mesothelin 2 ml Please note this test is not currently available. For further information or enquires please contact the Immunology laboratory 0117 4148366 Immunology
Special Precautions – Please click Test Name for further details 4 Urine - 24 hour Metadrenalines n/a 7 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Whole Blood Metadrenalines (Plasma) 4 mL 2 weeks Clinical Biochemistry
17 Plasma Methanol 5 mL 1 day Clinical Biochemistry
34 Fluids - e.g. CSF, vitreous Microscopy and Culture 200µL Microscopy mean 1 day Mycology Reference Laboratory
34 Bronchoalveolar lavage (BALs) and Sputums Microscopy and Culture 300µL Microscopy mean 1 day Mycology Reference Laboratory
34 Tissue - e.g. lung biopsy, corneal scraping Microscopy and Culture Microscopy mean 1 day Mycology Reference Laboratory
Microscopy for Crystals Cytology
24 Serum Mitochondrial antibody 2 mL 4 working days Immunology
35 Urine - Random MMA 5 mL 28 days Clinical Biochemistry
24 Serum MMA 2 mL 20 days Clinical Biochemistry
43 Swabs (nose and throat) Molecular assay (NAAT) Biofire Film array RP2 0.5 4 hours from receipt. Virology
Special Precautions – Please click Test Name for further details 24 Serum Moxifloxacin <3 days Antimicrobial Reference Laboratory
14 Bone Marrow MRD Flow Cytometry 0.5 mL 1 working day Immunology
35 Urine - Random Mucopolysaccharide screen 5 mL 14 days Clinical Biochemistry
34 Fluids - e.g. CSF, vitreous Mucorales PCR 100µL (Minimum) Mean 3 days Mycology Reference Laboratory
34 Tissue - e.g. lung biopsy, corneal scraping Mucorales PCR 100µL (Minimum) Mean 3 days Mycology Reference Laboratory
24 Clotted blood samples Mucorales PCR 200µL (Minimum) Mean 3 days Mycology Reference Laboratory
34 Bronchoalveolar lavage (BALs) Mucorales PCR 100µL (Minimum) Mean 3 days Mycology Reference Laboratory
24 Clotted blood sample Mumps IgG 0.17 4 days Virology
23 Skin Mycology
Skin Scrapings
n/a 15 days Microbiology
23 Hair Mycology Hair n/a 15 days Microbiology
23 Nail clippings Mycology Nail n/a 15 days Microbiology
Special Precautions – Please click Test Name for further details 14 Whole Blood Mycophenolate 4 mL 14 days Clinical Biochemistry
45 Aptima Swab or urine with a Copan or virocult swab Mycoplasma Genitalium 1 tube 3 days Virology
43 Swabs (nose and throat) Mycoplasma pneumoniae
Molecular assay (NAAT) Biofire Film array RP2
0.5 4 hours from receipt. Virology
Myoglobin - Urine
24 Serum Myositis line blot 2ml 2 weeks Immunology
34 Urine - Random NAG: Creatinine ratio                        1 mL 4 weeks Clinical Biochemistry
1 Aptima Swab Neisseria gonorrhoeae
NAAT
1 tube 3 days Virology
38 Aptima Urine Neisseria gonorrhoeae
NAAT
1 tube 3 days Virology
44 Whole Blood Neonatal Blood Group 1 mL 24 hours Blood Transfusion
44 Whole Blood Neonatal Crossmatch - Blood Transfusion 1 mL See Notes Blood Transfusion
44 Whole Blood Neonatal DAT 1 mL 24 hours Blood Transfusion
Special Precautions – Please click Test Name for further details 24 Serum Neuron Specific Enolase 5 mL 3 days Clinical Biochemistry
24 Serum Neuronal Antibody (Purkinje) 2 mL 14 working days Immunology
Special Precautions – Please click Test Name for further details 14 Plasma Neurotensin 5 mL 28 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 32 CSF Neurotransmitters see notes 4 - 6 weeks Clinical Biochemistry
Special Precautions – Please click Test Name for further details 20 Whole Blood Neutrophil Function Tests 7 mL 2 working days Immunology
9 Blood spot Newborn Screen 4x Spots Clinical Biochemistry
11 Faecal sample Norovirus PCR
pea sized amount 2 days Microbiology
24 Serum NT-Pro-BNP 5 mL 1 day Clinical Biochemistry
24 Serum Oestradiol 5 mL 1 day Clinical Biochemistry
Special Precautions – Please click Test Name for further details 25 Serum and CSF Oligoclonal bands 200ul CSF, 200ul Serum 5 working days Immunology
34 CSF Orexin 2mL 42 days Clinical Biochemistry
35 Urine - Random Organic acids 5 mL 14 days Clinical Biochemistry
35 Urine - Random Orotic acid 5 mL 14 days Clinical Biochemistry
35 Urine - Random Osmolality 5 mL Hospital patients 8 hours; GP patients 24 hours Clinical Biochemistry
24 Serum Osmolality 5 mL Hospital patients 8 hours; GP patients 24 hours Clinical Biochemistry
11 Faeces/ Urine Ova Cysts & Parasites Faeces/ Urine - Concentrate Minimum volume: 1/3 full/10ml minimum 4 days Microbiology
24 Serum Ovarian Antibody 2 mL 21 working days Immunology
Special Precautions – Please click Test Name for further details 14 Plasma Oxalate 5 mL 14 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 4 Urine - 24 hour Oxalate n/a 7 days Clinical Biochemistry
24 Serum Pancreatic Islet Cell Antibody 2 mL 14 working days Immunology
Special Precautions – Please click Test Name for further details 14 Plasma Pancreatic Polypeptide 5 mL 28 days Clinical Biochemistry
34 Tissue - e.g. lung biopsy, corneal scraping Panfungal PCR 100µL (Minimum) Mean 3 days Mycology Reference Laboratory
24 Clotted blood samples Panfungal PCR 200µL (Minimum) Mean 3 days Mycology Reference Laboratory
34 Fluids - e.g. CSF, vitreous Panfungal PCR 100µL (Minimum) Mean 3 days Mycology Reference Laboratory
24 Serum Paracetamol 5 mL 4 hours Clinical Biochemistry
34 Nasopharayngeal aspirates (NPAs) Paraflu 1
Molecular assay (NAAT)
0.5 2 days Virology
34 Bronchoalveolar lavage (BALs) and Sputums Paraflu 1
Molecular assay (NAAT)
0.5 2 days Virology
34 Nasopharayngeal aspirates (NPAs) Paraflu 2
Molecular assay (NAAT)
0.5 2 days Virology
34 Bronchoalveolar lavage (BALs) and Sputums Paraflu 2
Molecular assay (NAAT)
0.5 2 days Virology
43 Swabs (nose and throat) Paraflu 2
Molecular assay (NAAT)
0.5 2 days Virology
34 Bronchoalveolar lavage (BALs) and Sputums Paraflu 3
Molecular assay (NAAT)
0.5 2 days Virology
34 Nasopharayngeal aspirates (NPAs) Paraflu 3
Molecular assay (NAAT)
0.5 2 days Virology
43 Swabs (nose and throat) Paraflu 3
Molecular assay (NAAT)
0.5 2 days Virology
43 Swabs (nose and throat) Paraflu 4
Molecular assay (NAAT)
0.5 2 days Virology
34 Nasopharayngeal aspirates (NPAs) Paraflu 4
Molecular assay (NAAT)
0.5 2 days Virology
34 Bronchoalveolar lavage (BALs) and Sputums Paraflu 4
Molecular assay (NAAT)
0.5 2 days Virology
43 Swabs (nose and throat) Paraflu1
Molecular assay (NAAT)
0.5 2 days Virology
24 Serum Paraneoplastic line blot 2ml 2 weeks Immunology
34 Amniotic fluid Parvovirus
PCR (In house)
0.2 3 days Virology
14 EDTA Blood sample Parvovirus
PCR (In house)
0.45 3 days Virology
24 Clotted blood samples Parvovirus IgG and IgM Parvovirus IgG 0.17mL, Parvovirus IgG and IgM 0.19mL 4 days Virology
Special Precautions – Please click Test Name for further details 24 Serum Phenobarbitone 5 mL 1 day Clinical Biochemistry
9 Blood spot Phenylalanine 2x Spots 5 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Phenytoin 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
4 Urine - 24 hour Phosphate n/a 3 days Clinical Biochemistry
24 Serum Phosphate 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
20 Plasma Phytanic acid 2 mL 21 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum PIIINP 2 mL 4-6 weeks Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Piperacillin <3 days Antimicrobial Reference Laboratory
Special Precautions – Please click Test Name for further details 13 Plasma PIVKA II 10 days Haematology
34 Bronchoalveolar lavage (BALs) PJP PCR 100µL (Minimum) Mean 3 days Mycology Reference Laboratory
14 Whole Blood Plasma Viscosity 4 mL 3 days Haematology
14 Whole Blood Platelet count (EDTA & Citrate) 4 mL 24 hours Haematology
14 See Notes PNH Immunophenotyping 3 mL 4 working days Immunology
Special Precautions – Please click Test Name for further details 14 Whole Blood Porphyrin Enzyme/DNA analysis 4 mL 28 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 11 Faeces Porphyrins 5 g 15 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Whole Blood Porphyrins 5-10 mL 15 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 34 Urine - Random Porphyrins 10 mL 15 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details Serum Posaconazole < 2 days Antimicrobial Reference Laboratory
24 Serum Potassium 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
5 Urine Potassium n/a 1 day Clinical Biochemistry
24 Serum Prednisolone 5 mL 21 days Clinical Biochemistry
24 Serum Progesterone 5 mL 1 day Clinical Biochemistry
24 Serum Prolactin 5 mL 1 day Clinical Biochemistry
35 Urine - Random Protein 5 mL 1 day Clinical Biochemistry
34 CSF Protein 2 mL 4 hours Clinical Biochemistry
24 Fluid Protein 5 mL 3 days Clinical Biochemistry
24 Serum Protein 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
34 Dialysate Protein 5 mL 8 hours Clinical Biochemistry
13 Whole Blood Protein C 3 full tubes 21 days Haematology
13 Whole Blood Protein S 3 full tubes 21 days Haematology
13 Whole Blood Prothrombin Gene Mutation 3 full tubes 1 month Haematology
24 Serum PSA 5 mL 1 day Clinical Biochemistry
14 Plasma PTH 5 mL 1 day Clinical Biochemistry
32 PTH-related peptide Clinical Biochemistry
Special Precautions – Please click Test Name for further details 35 Urine - Random Purine / Pyrimidine Screen 5 mL 21 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Plasma Pyruvate Kinase 21 days Haematology
Special Precautions – Please click Test Name for further details 32 See Notes Quantiferon 7 working days Immunology
24 Serum RAST 2 mL Immunology
14 Whole Blood Red Blood Count 4 mL 24 hours Haematology
Red cell Transketolase
14 Plasma Renin 5 mL 28 days Clinical Biochemistry
43 Swabs (nose and throat) Respiratory Syncytial Virus
Molecular assay (NAAT)
0.5 2 days Virology
34 Nasopharayngeal aspirates (NPAs) Respiratory syncytial virus
Molecular assay (NAAT)
0.5 2 days Virology
34 Bronchoalveolar lavage (BALs) and Sputums Respiratory Syncytial Virus
Molecular assay (NAAT)
0.5 2 days Virology
14 Whole Blood Reticulocytes 4 mL 24 hours Haematology
Special Precautions – Please click Test Name for further details 34 Urine - Random Retinol Binding Protein 20 mL 14 days Clinical Biochemistry
24 Serum Rheumatoid Factor 2 mL 3 working days Immunology
43 Swabs (nose and throat) Rhinovirus
Molecular assay (NAAT)
0.5 2 days Virology
34 Bronchoalveolar lavage (BALs) and Sputums Rhinovirus
Molecular assay (NAAT)
0.5 2 days Virology
34 Nasopharayngeal aspirates (NPAs) Rhinoviurs
Molecular assay (NAAT)
0.5 2 days Virology
Special Precautions – Please click Test Name for further details 24 Serum Rifabutin <3 days Antimicrobial Reference Laboratory
Special Precautions – Please click Test Name for further details 24 Serum Rifampicin <3 days Antimicrobial Reference Laboratory
13 Whole Blood Ristocetin Co Factor. 2.7 mL 21 days Haematology
14 Whole blood Rituximab 3ml 2 working days Immunology
11 Faecal sample Rotavirus
PCR
pea sized amount 2 days Microbiology
24 Clotted blood samples Rubella IgG and IgM Parvovirus IgG 0.17mL, Parvovirus IgG and IgM 0.19mL 4 days Virology
24 Serum Salicylate 5 mL 4 hours Clinical Biochemistry
24 Serum Salivary Gland Antibodies 2 mL 21 working days Immunology
11 Faecal sample Sapovirus
PCR
pea sized amount 2 days Microbiology
24 Serum Selenium 5 mL 7 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 5 Urine - 24 hour Selenium n/a 14 days Clinical Biochemistry
24 Serum Serum Electrophoresis 2 mL 5 working days Immunology
24 Serum SHBG 5 mL 7 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Short Synacthen Test 5 mL 1 day Clinical Biochemistry
35 Urine - Random Sialic acid 5 mL 14 days Clinical Biochemistry
14 Whole Blood Sickle Cell Screen 4 mL 24 hours (confirmatory testing); 1 hour (urgent and request phoned through to lab) Haematology
14 Whole Blood Sirolimus 4 mL 3 days Clinical Biochemistry
24 Serum Skeletal Muscle Antibody 2 mL 21 working days Immunology
24 Serum Skin Antibody (Pemphigus/Pemphigoid) 2 mL 14 working days Immunology
24 Serum Smooth Muscle Antibody 2 mL 4 working days Immunology
24 Serum Sodium 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
35 Urine - Random Sodium 5 mL 1 day Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Plasma Somatostatin 5 mL 28 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 5 Urine - 24 hour Steroid Profile (urine) n/a 14 days Clinical Biochemistry
34 Stone Stones - Renal Calculi n/a 14 days Clinical Biochemistry
24 Clotted blood sample Streptococcus serology (antistreptolysin O)
ASO
0.15 6 days Virology
Special Precautions – Please click Test Name for further details 24 Serum Streptomycin <3 days Antimicrobial Reference Laboratory
Special Precautions – Please click Test Name for further details 24 Serum Sulphamethoxazole in Co-trimoxazole <3 days Antimicrobial Reference Laboratory
Special Precautions – Please click Test Name for further details 24 Serum Sulphonylurea 5 mL 28 days Clinical Biochemistry
24 Clotted blood samples Syphilis
RPR
0.5 4 days - Confirmations Virology
24 Clotted blood samples Syphilis confirmation testing - IgG and IgM; Treponemal serology 0.5 4 days - Confirmations Virology
43 Copan swab Syphilis PCR 1 tube 10 days Virology
24 Clotted blood sample Syphilis serology
Total Antibody - Screening
0.5 3 days - Screen Virology
24 Serum Systemic Sclerosis line blot 2ml 2 weeks Immunology
14 Whole Blood T Cell Subsets (see CD4 Counts) 3 mL 1 working day Immunology
Special Precautions – Please click Test Name for further details 14 Whole Blood Tacrolimus 4 mL 3 days Clinical Biochemistry
39 Whole Blood TB (Mycobacterium Blood) 3-5 mL 70 days Microbiology
6 Urine TB (Mycobacterium Urine) 250 mL 70 days Microbiology
34 Sputum/ Pus/ Tissue, NOT Swabs TB (Mycobacterium) samples (other than Blood/ Urine) n/a 70 days Microbiology
Special Precautions – Please click Test Name for further details 24 Serum Teicoplanin <2 days Antimicrobial Reference Laboratory
24 Serum Testis Antibody 2 mL 21 working days Immunology
Special Precautions – Please click Test Name for further details 24 Serum Testosterone 5 mL 1 day Clinical Biochemistry
24 Serum Testosterone confirmation 1 mL 14 days Clinical Biochemistry
24 Serum Tetanus antibodies 2 mL 28 working days Immunology
24 Serum TFT confirmation 1 mL 3 weeks Clinical Biochemistry
24 Serum Theophylline 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Whole Blood Thiopurine Metabolites 4 mL 21 days Clinical Biochemistry
14 Whole Blood Thiopurine methyl transferase 4 mL 14 days Clinical Biochemistry
0 Rectal suspension kit Threadworm 4 days Microbiology
Special Precautions – Please click Test Name for further details 13 Whole Blood Thrombophilia Screen 3 full tubes 21 days Haematology
24 Serum Thyroglobulin 5 mL 7 days Clinical Biochemistry
24 Serum Thyroid Function Tests 5 mL 1 day Clinical Biochemistry
24 Serum Thyroid Peroxidase Antibody 2 mL 7 days Clinical Biochemistry
24 Serum Tissue Transglutaminase Antibody 2 mL 7 working days Immunology
Special Precautions – Please click Test Name for further details 24 Serum Tobramycin <1 day Antimicrobial Reference Laboratory
Special Precautions – Please click Test Name for further details 24 Serum Total Bile Acids 5 mL 1 day Clinical Biochemistry
24 Serum Total Protein 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
24 Clotted blood samples Toxoplasma
Total antibody & IgM
0.5 5 days Virology
24 Serum Transferrin Glycoforms 5 mL 14 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 16 Whole Blood Transfusion Reaction 6ml 24 hours Blood Transfusion
1 Aptima Swab Trichomonas vaginalis
NAAT
1 tube 3 days Virology
24 Serum Triglycerides 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Trimethoprim in Co-trimoxazole <3 days Antimicrobial Reference Laboratory
4 Urine - 24 hour Trimethylamine n/a 8 weeks Clinical Biochemistry
24 Serum Troponin I 5 mL 4 hours Clinical Biochemistry
9 Blood spot TSH 2x Spots 7 days Clinical Biochemistry
24 Serum TSH Receptor Antibodies 2ml 8 working days Immunology
24 Serum U/E  (Urea and Electrolytes) 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
24 Serum Urate 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 3 Urine - 24 hour Urate n/a 1 day Clinical Biochemistry
24 Serum Urea 5 mL Hospital patients 4 hours; GP patients 24 hours Clinical Biochemistry
5 Urine Urine Electrolytes n/a 1 day Clinical Biochemistry
35 Urine - Random Urine Electrophoresis 1 mL 5 working days Immunology
Special Precautions – Please click Test Name for further details 5 Urine - 24 hour Urine Free Cortisol n/a 2-3 weeks Clinical Biochemistry
Urine reducing substances
5 Urine Urine Urea n/a 1 day Clinical Biochemistry
5 Urine - 24 hour Urine volume n/a 2 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Valproate 5 mL 7 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 24 Serum Vancomycin 5mL Hospital patients 4 hours Clinical Biochemistry
43 Vesicle Swab Varicella zoster
PCR (In house)
0.5 4 days Virology
34 Lesion/vesicle fluid Varicella zoster
PCR (In house)
0.5 3 days Virology
34 CSF Varicella Zoster
PCR (In house)
0.2 3 days Virology
14 EDTA Blood sample Varicella zoster
PCR (In house)
0.45 3 days Virology
24 Clotted blood samples Varicella zoster IgG 0.17 3 days Virology
24 Serum VEGF 2 mL 21 days Clinical Biochemistry
20 Plasma Very long chain fatty acids 2 mL 21 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Plasma VIP 5 mL 28 days Clinical Biochemistry
Whole Blood Viral Haemorrhagic Fever 7 mL 1 day Virology
0 Various Virology/ Serology (referred tests) n/a 10 days Virology
24 Serum Vitamin A 2 mL 14 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Whole Blood Vitamin B1 4 mL 2 weeks Clinical Biochemistry
24 Serum Vitamin B12 5 mL 3 days Clinical Biochemistry
Special Precautions – Please click Test Name for further details 14 Whole blood Vitamin B6 4 mL 3 weeks Clinical Biochemistry
Special Precautions – Please click Test Name for further details 20 Plasma Vitamin C 2 mL 4 weeks Clinical Biochemistry
24 Serum Vitamin D 5 mL 7 days Clinical Biochemistry
24 Serum Vitamin E 2 mL 14 days Clinical Biochemistry
35 Urine - Random VMA 5 mL 7 days Clinical Biochemistry
13 Whole Blood Von Willebrand's Disease 2.7 mL 3 weeks Haematology
Special Precautions – Please click Test Name for further details Serum Voriconazole < 2 days Antimicrobial Reference Laboratory
Special Precautions – Please click Test Name for further details 13 Plasma Warfarin levels 10 days Haematology
Special Precautions – Please click Test Name for further details 27 Serum and Urine Water Deprivation Test see notes 1 day Clinical Biochemistry
14 Whole Blood White Blood Count 4 mL 24 hours Haematology
Special Precautions – Please click Test Name for further details 14 Whole Blood White Cell Enzymes 5 mL 3-4 weeks Clinical Biochemistry
Special Precautions – Please click Test Name for further details 34 CSF Xanthochromia 1 mL 4 hours Clinical Biochemistry
Special Precautions – Please click Test Name for further details 10 Plasma Zinc 5 mL 7 days Clinical Biochemistry
Zinc Protoporphyrin

Medical Same Day Emergency Care (SDEC)

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Medical Same Day Emergency Care (SDEC) 

Medical Same Day Emergency care (SDEC) is situated at Gate 36, Level 1, within the Emergency Zone, Brunel building.

The Same Day Emergency Care Unit provides:

  • assessment
  • investigation
  • diagnosis
  • management of patients with an acute illness within 1 day.

The Same Day Emergency Care team consists of consultants, nurses, pharmacists, junior doctors, advanced practitioners, and physician associates. Support is provided to the team by specialist nurses and doctors in other specialties.

Analytes

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Benzylpenicilin (Penicillin G)

Gentamicin

As of 2nd December 2024, this test will be provided on the Clinical Biochemistry analytical platform, however clinical advice will still be offered by the Microbiology service 0117 4146222. Please see updated test information Gentamicin test page link.

Isoniazid (+ N-Acetyl-Isoniazid)

Sulphamethoxazole in (Co-trimoxazole)

Trimethoprim in (Co-trimoxazole)

Vancomycin

As of 2nd December 2024, this test will be provided on the Clinical Biochemistry analytical platform, however clinical advice will still be offered by the Microbiology service 0117 4146222. Please see updated test information Vancomycin test page link.

Antimicrobial Reference Laboratory Contact Details

Antimicrobial Reference Laboratory
Level 2, Phase 1, Pathology Sciences Building
Southmead Hospital
Westbury-on-Trym
Bristol
BS10 5NB

For General Enquiries and Results:

Telephone: 0117 4146269 or 0117 4146220
For Clinical Advice: 07802 720900
Email: arlenquiries@nbt.nhs.uk

Laboratory Hours

Monday to Friday 09:00 - 17:15

Saturday 09:00 - 12:00

Idiopathic Pulmonary Fibrosis (IPF)

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What is pulmonary fibrosis?

Pulmonary fibrosis is when normal lung tissue is replaced by scar tissue and/or inflammation. This makes the lungs stiff and not work as well.

  • Pulmonary is the medical term for your lungs.
  • Fibrosis means scarring.

We know what causes some types of pulmonary fibrosis. But sometimes we cannot find a cause, including in Idiopathic Pulmonary Fibrosis (IPF). We do know that it is not a form of cancer or cystic fibrosis, and it is not contagious.

How common is IPF?

IPF is rare - only around 14 to 43 people out of 100,000 have IPF. It can affect anyone but is much more common in older people.

What are the symptoms?

At first, people with IPF can have no or only mild symptoms. If the pulmonary fibrosis worsens then you may have:

  • Difficulty breathing.
  • Dry cough.
  • Feeling tired.
  • Poor appetite.

IPF can cause weight loss. You should weigh yourself regularly and speak to your GP or team if you are losing weight over time.

What tests will I have?

The doctors will take a detailed medical history from you and do a physical exam. You may also have the following tests:

  • Chest X-ray.
  • Lung function tests – to see how well your lungs work. They can also monitor how your condition is progressing. This may include a walking test to see how breathless you get.
  • CT scan – this will give us a detailed picture of your lungs including any scarring or inflammation.
  • Blood tests – to rule out other causes of pulmonary fibrosis.
  • If the diagnosis is still unclear, you might have surgery to take a lung biopsy (sample).

Will my lungs get worse?

In the past we thought all patients with IPF would get worse quickly. Now we know that some patients get worse more slowly, and some can stay the same for some time.

Unfortunately we cannot tell which patients will get worse and how quickly. This is an important area of research so we can understand this more and find better treatments.

If your symptoms change, that might mean your condition is getting worse. Speak to your respiratory team and mention any changes you have noticed.

If your symptoms suddenly get worse, speak to your GP.

How is IPF treated?

The fibrosis in IPF is permanent and cannot be cured but treatment can help slow progression or manage symptoms.

Medication

  • Your specialist might suggest you try medications to slow the scarring - antifibrotic medications.
  • They may suggest advise different medications to help your symptoms.

Pulmonary rehabilitation

  • Pulmonary rehabilitation is a supervised exercise and education programme.
    • It helps you manage breathlessness, stay active, and improve strength and energy.
    • The team may include physiotherapists, nurses, dietitians, and doctors.

Supplemental oxygen

  • Lung scarring can reduce the amount of oxygen that can get into your blood.
  • Some people may need oxygen therapy if oxygen levels in the blood are low.
  • This can improve breathlessness and help you stay active.

Clinical trials

  • You can ask about clinical trials which test new treatments. Joining is voluntary.

Lung transplants

  • A small number of patients may be referred for lung transplant assessment.

How can I help myself?

  • Have your seasonal vaccinations (COVID-19 and flu) and the pneumonia vaccination (only once).
  • You may be eligible for benefits like PIP (Personal Independence Payment) if you need help with personal care or getting about.
  • Our specialist nurses runs a regular Pulmonary Fibrosis Support Group which is a space for discussion with other patients with similar lung conditions. Here we also aim to have presentations from a variety of guest speakers and charities.
  • Keep active and do what you enjoy!

Resources and how to contact us

Resources

How to contact us

For ILD related queries:

© North Bristol NHS Trust. This edition published April 2026. Review due April 2029. NBT003582

Endoscopic Sleeve Gastroscopy (ESG)

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Welcome to the North Bristol Weight Management Service

This information is to help you prepare for your procedure. Take time to read it carefully, and we can answer any questions you have.

Important information:

  • We are here to help you on your weight loss journey and think surgery will help your health and wellbeing.
  • It is a big step, and we can help you make long-term habits to maintain your progress. We can support you for 2 years after surgery.
  • We cannot offer this procedure to anyone who smokes or vapes – nicotine causes complications.
  • We welcome your feedback and suggestions to improve our service.

Endoscopic Sleeve Gastroplasty (ESG)

  • ESG is an endoscopy procedure to reduce the size of the stomach.
  • We place stitches (sutures) on the inside of the stomach and pulling them tight to fold the stomach in on itself.
  • This means your stomach holds less food, and you will feel full more quickly after eating.
  • You will lose about 10-15% of your body weight usually in the first year.
  • Your change in appetite means you can start new eating habits along with help getting the right nutrition.
  • Endoscopic means we put a flexible tube down your throat to do the procedure. We won’t do any external incisions (cuts) so there are less complications than other types of weight loss surgery.

Complications

The risk of serious complications like these is small:

  • Bleeding.
  • Infection.
  • Tears in the stomach.
  • Abscess (a pocket of infection).
  • Leaking of stomach contents into the chest or abdominal cavity.
  • Pulmonary Embolism (a blood clot in the lung).
  • Pneumothorax (collapsed lung).

Diet before ESG

Many people who live with obesity have an enlarged liver. This can make the procedure more difficult and increase the risk of complications.

It is important you follow a low calorie and carbohydrate diet for 2 weeks before your operation. The diet helps shrink the size of the liver making the procedure easier and safer. It is sometimes called the Liver Reducing Diet.

This diet will encourage your body to use up its stores of glycogen (a form of stored sugar in the liver and muscles). This causes the liver to shrink rapidly.

This diet designed to reduce your risks from the surgery and should not be followed long term.

What does the diet involve?

  • Each day aim to stick to between 800-1000 calories. This should include at least 60-80g protein.
  • The diet is low calorie, low fat, low sugar, and low carbohydrate.
  • You can choose to use food, shakes or a combination of both.
  • We suggest you include at least 1 meal per day of normal food. This is so you can practice chewing your food thoroughly. You should chew each bite at least 20 times until it is soft/like a paste before swallowing.. This is an important part of eating after your surgery to make sure you get the best outcome.

Option 1: food

Protein: try to include a protein food at every meal. Aim for 60-80g protein each day. Focus on low-fat protein sources such as chicken, fish, turkey, beans, lentils, tofu, or low-fat dairy.

Fats: limit the amount of oil, butter or margarine you use. Cooking sprays are a good alternative. Try to avoid high-fat foods such as cakes, biscuits, or crisps.

Carbohydrate: Limit carbohydrates with lots of starch. Try to have 1-2 meals per day which do not include starchy carbohydrates. Choose wholegrain options if you do eat them. Aim for less than 120g per day.

Sugars: Avoid adding any type of sugar, honey, or syrup to foods. Artificial sweeteners are ok to use. Aim to avoid eating any foods high in sugar e.g. cake, chocolate, sweets, fruit juice.

You will need to start taking a multivitamin and mineral supplementation as this diet is won’t give you all the nutrients you need. This can be either tablet or chewable/gummy. There is more information about vitamins later in this booklet.

Meal ideas

BreakfastLunchDinnerSnacks
High protein yoghurtSoup with meat/beans/ lentilsChicken breast (no skin) with vegetables and 1-2 new potatoes

Boiled egg

Egg muffin

Babybel light  

High-protein yoghurt

Veg sticks

Fruit (1 portion) like 1 apple, 1 small banana, 2 satsuma/kiwi/ plum, 80g of chopped fruit  

Poached/ boiled eggs on 1 slice seeded bread1-2 oatcakes with cottage cheese and saladHomemade turkey burger with salad and low-fat coleslaw
150-200g Low-fat natural yoghurt with berriesTuna/chicken/tofu salad with low-fat salad dressingWhite fish or tuna steak with ratatouille
Scrambled eggs/tofu with mushrooms and tomatoes1 slice seeded bread with tuna/ chicken/tofu and sweetcorn mixed with low-fat mayoTurkey mince chilli with veg and 1-2 tablespoons of cooked brown rice
Protein shakeHummus or bean dip with vegetable sticksShakshuka - baked eggs in a tomato stew

Nutrient tracking options

Where to find recipes

Option 2: meal replacement shakes

You can have low-sugar, high-protein, meal-replacement shakes to provide 800-1000 calories in total each day. Many of these shakes are low in fibre so it can be helpful to include 1-2 portions of vegetable or salad each day (fibre in these helps prevent constipation).

Look for shakes with 200-300 kcals and 20-30g protein per serving. Aim for a low sugar option - about 5g of sugar per 100g/100ml.

Some suitable options

ProductPreparationNutrition per servingServings per day
High-protein milk2 tbsps of skimmed milk powder to 300ml milk

Skimmed milk:

215kcals and 21g protein

Semi-skimmed: 250kcals and 21g protein

3-4
Huel*

40g Huel black edition powder mixed with 500ml water

Huel black edition pre-made (500ml)

400kcals and 40g protein

400kcals and 35g protein

2-2.5
Grenade Carb Killa

Pre-made shakes (330ml)

Bar (60g)

210kcals and 25g protein

240kcals and 20g protein

3-4
My Protein

60g Impact diet whey powder mixed with 300ml water

Pre-made Impact shake (330ml)

220kcals and 35g protein

200kcals and 25g protein

3-4
PhD Smart protein Plant*25g powder in 250ml water

240kcals and 20g protein

220kcals and 21g protein

3-4

* vegan options

Option 3: combination of food and shakes

MealFood/shakeCalories (Kcal) per portion
BreakfastMeal replacement shake200-250 Kcals
LunchMeal replacement shake200-250 Kcals
Evening mealLunch/dinner option from meal ideas table above300-400 Kcals
SnacksVegetable sticks/sugar free jelly5-100 Kcals

Diabetes

If you have diabetes treated with tablet medication and/or insulin you will probably need to change these medications. Your diet before and after surgery will have very little carbohydrate and can increase your risk of hypoglycaemia.

We will help you make a plan in your pre-operative assessment appointment. You will need to monitor your diabetes control more closely during this time.

Reintroducing food after ESG

What is the aim of the diet after ESG (post-procedure diet)?

After your procedure you will reintroduce food over 6 weeks. You will slowly move from liquids to solid food. This is to reduce pressure in the gastric pouch, give the stitches time to heal, and optimise your weight loss.

Aim to:

  • Take small mouthfuls of food and drink.
  • Stop eating before you feel full - 1-2 mouthfuls of food extra may make you feel discomfort, nausea or make you vomit.
  • Learn what the early signs of fullness feel like to you and stop here.
  • Chew your food thoroughly – about 20 times per mouthful.
  • Sip fluids slowly.

If you do not follow these recommendations, there is a risk of loosening the stitches, becoming unwell, or not achieving significant weight loss.

The post-procedure diet involves 4 stages:

  1. Thin liquids: 2 days days 1-2)
  2. Liquid diet: 12 days (week 1-2)
  3. Puree diet: 2 weeks (week 3-4)
  4. Soft diet: 2 weeks (week 5-6)
  5. Normal texture food: week 7 onwards

Stage 1: thin liquids (2 days)

Following surgery, you will need to drink thin liquids (drinks) only for 2 days such water, squash, protein water, tea and coffee, and semi-skimmed milk.

  • Have small amounts of fluid (no more than 50mls) every 10-15 minutes.
  • Aim for least 2 litres of fluids each day.
  • Even if you feel thirsty it is important you drink small quantities at a time
  • Avoid fizzy or high sugar drinks such as juices.
  • If you have stomach pain or nausea whilst drinking stop until the feeling has passed.

Stage 2: liquid diet (12 days)

Aim to have high protein drinks, shakes, or soups which are smooth (with no lumps) regularly through the day. The liquids should be able to run off the back of a spoon like thin yoghurts, tinned soups, or runny custard.

  • Portion sizes are approximately 100-300ml.
  • Take small mouthfuls one at a time and give yourself a break in between mouthfuls so you can recognise the early signs of fullness and stop.
  • If you feel pain, stop immediately.
  • You will need to drink other fluids (water, tea, squash) to get your 2 litres fluids per day.
  • It can be difficult to get enough nutrients while you are following a liquid diet.
  • Aim to include as many liquids with lots of protein as possible. Protein is important for your general health including maintaining your muscle mass while you are losing weight. This will help your overall weight loss.
  • Aim for 60g protein.

High protein liquids

  • ‘Fortified milk’ - 1 pint semi-skimmed or skimmed milk with 4 tbsps of dried skimmed milk powder.
  • Smoothies – fruit or vegetables blended with fortified milk, natural yoghurt or protein powder. (Avoid shop bought smoothies as these are low in protein and high in sugar).
  • Smooth Soup (homemade or tinned). Add 1-2 tbsp of skimmed milk powder, protein powder or quark.
  • Meritene or Complan shakes or soups – available in Supermarkets or pharmacies.
  • Meal replacement shakes e.g. Slimfast, Tesco Slim, Asda Great Shape, Exante or Lighter Life.
  • High protein milkshakes e.g. UFit, Arla, For Goodness Shakes, Urban Active
  • Protein Water e.g. Vieve, Upbeat or +PW
  • Whey, soya, or pea protein powders

Recipes

OptionIngredientsMethod
High protein milk

4 tbsp (60g) skimmed milk powder

1 pint (570ml) skimmed or semi-skimmed milk

Optional vanilla extract/ unsweetened cocoa powder/coffee

Mix milk powder with a little milk to form a paste.

Stir in the rest of the milk.

Fruit smoothie

Half a pint (250ml) high protein milk

One quarter of a pint (100ml) low fat yoghurt

3 oz (100g) fresh fruit like banana, strawberries (fresh or frozen)

Combine all ingredients in a blender and blend until smooth.

Serve chilled

 

Stage 3: puree diet (2 weeks)

After 10 days of a liquid diet, you can progress to foods with a thicker, puree consistency. You will need to use a food blender, processor or liquidiser.

Start with 1 tsp of food at a time and check how you feel after. Each meal should have around 2- 4 tbsp. Aim to eat the protein part of the food first. It may be helpful at this stage to cook and freeze foods, as portions will be small.

See the example menu plan on the next page.

Tips:

  • Eat protein food first, then vegetables and finally carbohydrates. P.V.C (Protein, Vegetable, Carbohydrate). In the early days, you may only manage the protein.
  • Use high-protein milk in/with foods such as cereal, scrambled eggs etc.
  • Try one new food at a time. If you feel sick, gas, or bloated, it may be the case you are not ready for this type of food, try again in a few days.
  • Food can be liquidised in bulk and frozen. You can use an ice cube tray and take a few ice cubes out per meal.
  • Slow cook or casserole meat in plenty of liquid to make it easier to blend.
  • Adjust your portion sizes as you feel necessary. Listen to your body and stop before you feel full.

Sample meal plan

MealOptions
Breakfast
  • Half or 1 whole Weetabix with high protein milk or
  • 1 pot yoghurt of fromage frais or
  • 2 tbsp of porridge or Ready Brek made with high protein milk
Mid morning
  • 200 ml high protein drink
Lunch
  • 1 cupful of soup made with fish/meat/beans/ pulses and potato or
  • 1 scrambled egg or
  • 1-2 tbsp pureed fish/pulses/ chicken/meat or
  • 1-2 tbsp mashed cottage cheese or

with 1/2 tbsp pureed vegetables

and 1/2 tbsp mashed potato/sweet potato/winter squash

Mid afternoon
  • 150ml yoghurt with or without pureed fruit or
  • 150ml fruit smoothie or
  • 200ml skimmed or semi-skimmed milk or
  • 2 tablespoons low fat custard or
Evening meal

1-2 tbsp pureed fish/pulses/chicken/meat,

with ½ -1 tbsp blended vegetables,

  • and ½ -1 tbsp mashed potato/sweet potato/winter squash
Evening snack200ml high protein drink

Stage 4: soft diet (2 weeks)

You no longer need to blend food. Gradually introduce foods which are soft in consistency, that is they fall apart easily with a fork. Foods which are naturally moist are good at this stage or add sauce/gravy to dishes.

You can also include crunchy foods in this stage such as cereal, crackers or toast. Make sure you chew these foods thoroughly. Start with a small portion e.g. 3 tablespoons as a meal and increase gradually depending on how you feel.

Tips:

  • Aim to grill or air fry and use herbs/spices to flavour foods.
  • If using oil, measure out a small amount (1-2 tsp).
  • Try 1 tbsp (tablespoon) of a new food every 1-2 days. If you feel nauseated or bloated after eating, then you may not be ready for this food. Wait a few days before trying this food again.

Sample meal plan

MealOptions
Breakfast
  • 1 Weetabix/25g porridge oats/All Bran/Branflakes with skimmed or semi-skimmed milk or
  • Scrambled egg with 2 wholegrain crispbreads/ crackers with 1 tsp butter/margarine/low fat cheese spread
Mid morning
  • 150ml light natural yoghurt/fruit yoghurt or
  • 200ml semi-skimmed milk or
  • 200 ml high protein drink
Lunch
  • 200ml high protein soup for example chicken/lentil/ bean/fish or
  • Small jacket potato without skin with 40g cottage or low fat cheese or
  • Macaroni cheese/cauliflower cheese
Evening meal
  • 50g fish/chicken/turkey/ground beef
  • with half a cup soft cooked vegetables
  • and half a cup mashed potato/sweet potato/winter squash/risotto/4-6 wholegrain crackers/1 slice wholegrain toast
Evening snack
  • 150ml low fat natural or low sugar fruit yoghurt or
  • 1/2 cup pureed/stewed/soft/tinned fruit or
  • 1 scoop sorbet or
  • 200 ml high protein drink

 

Stage 5: healthy normal textured diet (week 7 onwards)

You are now ready to progress onto your long-term healthy diet.

This can be challenging as you learn how much you can eat of certain foods and the importance of paying attention to your body as you eat. Continue to add new foods in slowly. Aim to eat 3 small meals per day with 1-2 snacks as necessary. Focus each meal and snack on protein-rich foods. Keep portions small by using a side plate. Aim to eat 60-80g protein per day.

Cooking tips:

  • Remove fat and skin from meat before cooking.
  • Use low fat cooking methods such as grilling, baking (wrap in foil to keep things moist), steaming or boiling.
  • Limit oil or butter added to vegetables or salads. If you need extra flavour, add seasoning, low-calorie dressing or vinegar.
  • If you need to use oil to stop food from sticking, use a spray oil.
  • Add flavour using herbs, spices, seasonings, lemon juice, ginger, onions, and garlic.
  • Aim to avoid adding oil or butter to carbohydrates.
  • Choose high fibre (wholegrain) carbohydrate foods where possible like wholegrain bread, brown pasta, brown rice, wholegrain / seeded crackers or oatcakes and keep skins on potato.

Sample meal plan

MealOptions
Breakfast
  • Wholegrain cereal/porridge/Ready Brek made with milk or
  • Wholegrain toast/crackers/crispbread with 1 tbsp of low fat cheese spread/peanut butter/hoummous or
  • Scrambled egg on toast or
  • Baked beans on toast
Mid morning
  • Fruit, tea/coffee or
  • Cracker with low fat spreadable cheese/peanut butter
Lunch
  • 200ml high protein soup like chicken/lentil/bean or
  • Baked beans / sardines / poached egg on toast or
  • Bean and rice salad or
  • Small jacket potato with baked beans/tuna/cottage cheese
Dessert
  • 150ml light natural or fruit yoghurt or
  • Half a cup soft/pureed/stewed fruit or
  • 1 scoop sorbet
Mid afternoon
  • Tea/coffee/vegetable juice
  • Fruit/low fat yoghurt
Evening meal

Small serving of lean meat/fish/egg/beans/lentils/tofu/ quorn

with a serving of vegetables or salad

  • and small serving of potatoes/brown rice/brown pasta/ chapatti/yam/plantain/cassava
Dessert
  • Fruit/low fat yoghurt/low fat puddings

Snack ideas - 100 calories with high protein

  • Small handful nuts
  • Slice of smoked salmon or ham with cucumber sticks
  • Trail mix of nuts/seeds with dark choc chips
  • 1 pot of high protein natural yoghurt (Icelandic or low fat Greek style)
  • 1 pot Greek style Soya yoghurt
  • 1 boiled or Devilled egg
  • 1 oatcake or rye crispbread with 1 tbsp cottage cheese or low fat cream cheese
  • 1 egg muffin
  • Veg sticks with 1 tbsp of hummus or bean dip
  • 2 tbsp roasted pumpkin/ sunflower seeds
  • Slice smoked salmon with 1 teaspoon cream cheese
  • Nice cream – frozen banana whizzed with peanut butter
  • 1 pot of fruit flavoured high protein yoghurt
  • 2 tbsp low fat Greek yoghurt with handful of berries
  • 80g soya/edamame beans
  • 80g Spicy chickpeas – try roasting with cumin and smoked paprika
  • Slice of ham with low fat cheese spread* or cottage cheese
  • 1 mini cheese or Babybel
  • 1 stalk of celery or 2-3 slices of apple with 2 tsp of almond butter
  • 1 pack of chicken bites

Complications after the procedure

Constipation

It is common to have constipation in the early days after these operations because you are not having much food and drink

To help manage constipation:

  • Drink plenty of fluids – aim for 2 litres a day a day.
  • Add in a laxative such as sodium docusate or senna.
  • Add in some high fibre foods where able e.g. vegetables, wholegrain carbohydrates, beans and pulses.
  • Keep as active as you can.

Please contact the Bariatric Team or the Bariatric Clinical Nurse Specialist if the above does not work.

Nausea, vomiting, and indigestion

If you have any of these, it may be because you are:

  • Eating too quickly.
  • Not chewing enough.
  • Eating too much.
  • Drinking with the meal or within half an hour after eating.
  • Lying down too soon after eating.

If you suddenly feel unwell with symptoms such as shortness of breath, worsening abdominal pain, fever, limb swelling, unable to tolerate food/fluids, nausea and vomiting please go to the Emergency Department, contact Bariatric Team or GP.

Feeling tired

It is common for people to feel tired and to have low energy levels in the early weeks after the procedure. This is usually because it is difficult to get enough calories and protein, also the fact you are losing weight.

Aim to consume at least 60g protein and 800 calories each day. If you are struggling to do this, it can be helpful to include protein shakes to help meet this target.

Tiredness can also, but less commonly, be due to a vitamin or mineral deficiency, so please do ensure you take your multivitamin and mineral supplement once a day.

Hair loss

In the first 6-9 months, it is common to have some hair loss. This also is usually due to not enough calories and protein. Once your weight loss has stopped, this problem usually goes away.

Vitamin and mineral deficiencies

After your procedure you will be eating much smaller portions of food and it can be hard to get all the vitamins and minerals your body needs. Please take the following vitamins and minerals. You can buy these in most supermarkets, chemists, or online.

  • 1 A-Z multivitamin tablet once a day.
  • 1 vitamin D tablet once a day.

For first 6 weeks these need to be in a chewable form. Once you are on a normal textured diet you can take a tablet form.

Suitable options are:

  • Chewable: Superdrug chewable, Centrum chewable
  • Tablet: Tesco A-Z, Superdrug A-Z or Aldi A-Z

Dumping syndrome

Dumping syndrome is a less common side effect after ESG. It happens when the lower end of the small intestine (the jejunum) fills too quickly with undigested food from the stomach. There are two types of dumping:

  • Early dumping - happens during or right after a meal. Symptoms of early dumping include nausea, vomiting, bloating, cramping, diarrhoea, dizziness and fatigue
  • Late dumping - happens 1-3 hours after eating and is usually due to a low blood sugar. Symptoms of late dumping include weakness, sweating and dizziness .

Managing dumping syndrome

  • Early dumping syndrome: lie down as soon as you have symptoms, you are likely to feel better after around 30 minutes.
  • Late dumping syndrome: have a snack that includes both carbohydrate and protein like a cracker with soft cheese. If you feel very unwell you may need a small glass of orange juice before the cracker to bring your blood sugar back to normal.

To avoid dumping symptoms:

  • Avoid chocolate, biscuits, cakes, sweets, desserts, high sugar drinks, high glycaemic index (GI) carbohydrates such as white bread.
  • Aim to eat at least 3 times per day (rather than 1 big meal).
  • Avoid eating and drinking at the same time – wait 20 minutes.

Increased fertility

Losing weight can increase fertility and we strongly recommend that you do not become pregnant for at least 18 months following the procedure. Weight loss can have negative effects on the pregnancy.

After this surgery your oral contraceptives (the pill) may not work. You should use alternative methods of contraception, for example, barrier methods (condoms/cups) if this is a concern.

If you become pregnant following the procedure it is important to let your GP, Obstetrician, Midwife, and Bariatric Team know as soon as possible. You may need extra monitoring during the pregnancy to make sure that you and the baby get enough nutrients to keep healthy.

Long term tips for the best outcome

  1. Focus on protein-rich foods every time you eat. Include vegetables, salads, wholegrain carbohydrates, unsalted nuts and fruit.
  2. Eat three meals a a day and choose healthy snacks if you are hungry in between meals.
  3. Think PVC – protein first, then vegetables, then carbohydrates.
  4. Limit foods high in fat, saturated fat and sugar such as biscuits, cakes, muffins, sweets, confectionary, chocolate and crisps
  5. Aim to follow the ‘Rule of 20’:
  6. Cut your food up to the size of a 20 pence piece size
  7. Chew 20 times
  8. Wait for 20 seconds after swallowing before taking a second mouthful.
  9. Stop eating after 20 minutes (if you haven’t already stopped).
  10. Avoid drinking 20 minutes before and after eating
  11. Sip fluids often throughout the day; aiming for 2 litres a day
  12. Avoid carbonated and sugary drinks.
  13. Avoid alcohol for the first 6 months and drink within recommended a day limits thereafter.
  14. Monitor your weight and food intake if you find this helps you keep on track.
  15. Move your body in ways that your body allows, and you enjoy such as exercise classes, walking or dancing in the kitchen.
  16. Take your vitamin and mineral supplements.

You will have Specialist Dietician support for 2 years following the procedure. Your first review will be approximately 4 weeks after your operation.

How to contact us

  • Bariatric Coordinators: 0117 414 0855/54
  • Bariatric Waiting List Coordinator: 0117 414 8826
  • Bariatric Surgery Senior Enhanced Practitioner: 0117 414 2085 or 0755 7312784

© North Bristol NHS Trust. This edition published April 2026. Review due April 2029. NBT003687