Haematology Test and Platform Changes

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Our new Coagulation Screening and Haematology platforms are live.

Whilst the majority of reference ranges will stay the same, some are quite different. Specific protocols and reference range information is displayed below.

Analyte

 

Current NBT Adult Reference RangeNEW ADULT REFERENCE RANGE FROM 24/04/2023
APTT21.0 – 33.0 secs25-37 secs
Clauss Fibrinogen1.5 – 4.0 g/L2-4 g/L
D-Dimer< 0.50 ug/mL FEU< 500 ug/L FEU (Age adjusted D-Dimer range)

For Special Coagulation tests (Thrombophilia, Lupus Anticoagulant and Factor Assays), relevant comments will be added to results as appropriate.

Please note that Paediatric ranges have not changed.

Haemoglobinopathy change in platform:

As of as of 18/12/2023, the first line haemoglobinopathy testing analytical method has changed. It is approved for use in sickle cell and thalassaemia (SCT) screening programme and has been verified in-house at NBT

The new reference range will therefore start at 90% (change from 80%). The previous method separated some HbA fractions, which no longer applies to the new method, but this has no impact on the interpretation of results. 

HbA2 values are comparable across platforms and reference ranges and interpretation have not changed.

HbF less than 0.3% is not detectable on the new analyser and results less than this will therefore be reported as HbF <0.3%.

There will be no changes to the way that haemoglobin variants and thalassaemias (carriers and disease) are reported.

Test accreditation

We are updating both our test information pages Test Information and the quality section Pathology Accreditation and Compliance Status with details of assays affected.

All the tests, which were previously accredited by UKAS, will be going under an Extension to Scope process. However, please be assured that the quality of our services will remain the same.

If you have any concerns or queries, please contact us (https://www.nbt.nhs.uk/severn-pathology/pathology-services/haematology/contact-haematology).

Test Information

Sample vials for testing

Includes details of sample types, volumes, special precautions, turnaround times & reference ranges.

Letter Regarding Accreditation of Haematology Tests and Managed Service.pdf

Researcher webinars

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A recorded webinar series organised by the South West Developing a Research Skilled Workforce Team 

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The SNAHPer group are delighted to share with you a series of recorded webinars,  to help you think, plan and develop your research-related activities. 

 

Webinar 1 - Demystifying Research

Webinar 2 - Using Evidence to change practice

Webinar 3 - Do I matter to research

Webinar 4 - Designing your roadmap to success

Webinar 5 - Sharing is caring

Webinar 6 - There's no 'I' in Team

 

View Our Research

Doctor conducting research at NBT

Explore the ground-breaking research currently taking place at North Bristol NHS Trust.

About Research & Development

NBT Researcher

Find out more about our research and how we're working to improve patient care.

Contact Research

Research & Development
North Bristol NHS Trust
Level 3, Learning & Research building
Southmead Hospital
Westbury-on-Trym
Bristol, BS10 5NB

Telephone: 0117 4149330
Email: research@nbt.nhs.uk

Enhanced Recovery After Gynaecology Surgery

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Welcome to the Enhanced Recovery Programme

This information aims to increase your understanding of how to be an active part of your own recovery after surgery. If there is anything that you are unsure about, please ask. It is important that you understand the programme, so that you, your family and friends can be involved.
This is the programme offered by North Bristol NHS Trust for patients undergoing planned gynaecology surgery. There may be circumstances where the programme will not be appropriate for some patients and if this is the case, you will be fully informed of the alternatives.

What is the Enhanced Recovery Programme?

The Enhanced Recovery Programme is to get you back to full health as quickly as possible after your operation. The hyperlink below will take you to a short video about Enhanced Recovery called "Fitter Better Sooner". We strongly encourage you to watch the video:

Fitter, Better, Sooner Toolkit | Centre for Perioperative Care (cpoc.org.uk)

Research indicates that after surgery, the earlier you get you out of bed, exercise, eat and drink, your recovery will be quicker and with less risk of complications. Some of the benefits include:

  • A quicker return to normal bowel function
  • Reduce chest infections
  • A quicker return to usual mobility.
  • Decreased fatigue
  • Reduced risk of developing blood clots after surgery

To achieve this, we need you to be partners with us working together to speed up your recovery.

What will happen? 

Before you come into hospital

The medical staff will see you in the outpatient’s department to explain your operation. Following this you will be sent a date to attend the pre-operative assessment clinic, where trained staff will carry out routine tests that are required to ensure you are fit and safely prepared for surgery.

When you attend the preoperative assessment clinic, we will explain the programme to you and your family. You will be provided with written information, time to ask questions and may be referred to the anaesthetist. The nurse will discuss your arrangements at home so that together we can plan for any help you may need after your operation. All patients are screened for potential infections at this appointment.

We will discuss diet and exercise with you and if necessary, you will be referred to the dietician. For example, if you have lost a lot of weight or your appetite is poor.

It is important to keep as active as you can before your operation and if you are a smoker you should stop now. This helps reduce breathing problems after surgery. You can see your GP or pharmacist for advice on products to help you stop smoking.

Please bring: 

  • A supply of your own medication (these will be stored safely on the ward and returned to you when you go home). 
  • A dressing gown, or similar item of clothing (as there is evidence to suggest that keeping warm before surgery helps prevent infection) 
  • A supply of comfortable day clothes (as you will be encouraged to return to ‘normality’ as quickly as possible after your operation).

Eating and Drinking – before surgery

Prior to your surgery you will be able to eat and drink as normal unless you are required to take medication to clear the contents of your bowel. If this applies to you it will be discussed with you at pre operative assessment. It is important to have a variety of non-fizzy drinks during your hospital stay.

You may continue to eat for up to six hours before your operation and drink clear fluids for up to two hours before.

Preparing for surgery

To help prevent blood clots you will be required to wear special support stockings (TEDS). The nurse will measure your legs to choose? the correct size. You will also be given an injection called ‘clexane’ in the evening. This helps reduce the risk of blood clots by thinning the blood. The injection will be given each day you are in hospital. 

Some patients at higher risk of experiencing blood clots may need to continue the injection at home. This would only be temporary and will be discussed with you when you are in hospital. Most patients can inject themselves or with the help of a relative or carer. The nurses on the ward will show you how to do the injection. If you have problems with giving yourself the injection we will arrange for a District Nurse to visit you. 

For those also having an operation on their bowel: You may need an enema to empty your bowel contents on the day of your operation. After an enema, it is important to drink plenty to replace any fluid lost. Some patients may have to take medication the day before to achieve this (if this applies to you more information? will be given). 

It is very important to keep yourself warm before your operation and you are advised to dress accordingly (warm dressing gown, socks, slippers, blankets etc.) When it is time for your operation you will be required to wear a hospital gown.

 

After your operation 

DrEaMing (Drinking, Eating, and Mobilising) after your operation 

You may hear the staff on the ward talk about “dreaming”. They are not talking about what happens when you are asleep! In fact, they are talking about some of the most important components to successful recovery after surgery- Drinking, Eating and Mobilising also known as DrEaMing. We know that if you can “DrEaM” within 24 hours of your surgery, you will be on track to recover quicker, sooner and better. 

To help you with this we will create a rhythm to your day that follows the pattern of eating a meal in a chair, mobilising, then resting. 

Drinking and eating

It is important to start drinking and eating as soon as you can after surgery. Initially some patients may find a low fibre diet more tolerable. We encourage you to sit out of bed for your meals to help build your strength and mobility. 

Studies show that chewing gum after surgery can improve your recovery by assisting the bowel to return to normal. Chewing gum can also help disperse trapped wind that can sometimes occur after surgery. We advise that on the day you come into hospital, you bring chewing gum with you. After your operation chew gum for 15 minutes, a few times a day, until your bowel function returns to normal.                                                                                                   

Mobilising

Staff will help you out of bed about six hours after your operation. We encourage you to eat all your meals sitting in a chair. After your meals we suggest that you move around the ward as you are able. The staff on the ward will assist with this if required. After this gentle exercise, it is important to return to bed for some rest. 

Following your operation, it is important that you do deep breathing exercises to prevent chest infection. You will need to do deep breathing exercises every hour. To do these you will need to:

  • Be in an upright position.
  • Take a deep slow breath in (feel your stomach gently rise). 
  • Hold the breath for 3 seconds. 
  • Breathe out slowly. 
  • Repeat 5 times.

You should cough regularly to make clear your lungs of secretions. To do this, place a towel or pillow over your incision site, support it with your hands and cough. 

When you are sitting in the chair or lying in bed, you should do frequent leg exercises as prevention against blood clots. To do this point your feet up and down and move your ankles as if making circles. 

By being out of bed in a more upright position and by walking regularly, lung function is improved and there is less chance of a chest infection after surgery. Circulation is also improved, reducing the risk of blood clots and helping bowel function return to normal. 

Try and wear your day clothes after your operation as this can help you feel positive about your recovery.

Below is a video of some examples of breathing and leg exercises: 

Pain Control

It is important that your pain is controlled so that you can walk about, breathe deeply, eat and drink, feel relaxed and sleep well.

Various tablets can be used for pain for example paracetamol, ibuprofen, codeine and morphine (liquid or injections, as needed). Pain control is really important, and there are additional ways of giving painkillers if the above medicines are not sufficient. You will need to take your painkillers regularly (three or four times per day) to make sure you are comfortable.  

If you are uncomfortable or in pain, then please tell the nursing staff immediately and they will be able to help you.

Sickness

After an operation and anaesthetic it is not uncommon to feel nauseated and vomit. You will be given medication during surgery to reduce this. If you feel sick following surgery please tell a member of staff who will be able to give you something for this.

Tubes and Drips

We will want to make sure that you are able to pass urine after your surgery. If we are concerned that this may be 
difficult due to your operation, a tube (catheter) may be placed into your bladder so that we can check that your kidneys are working well and your urine output can be measured. If you have a catheter, it will be removed as soon as possible. 

You will have an intravenous drip put into your arm to ensure you do not become dehydrated. The drip will normally be removed the day after surgery, but you may still have the intravenous port (venflon) in case we have to give other drugs through it. You may also be required to breathe extra oxygen for a short while after your operation.

Vaginal bleeding

It is normal to have vaginal bleeding after gynaecological operations. This bleeding may be like a light period. Tampons must not be used for bleeding after surgery.

Monitoring

Many different things will be monitored during your treatment including:

  • Observations (oxygen levels, breathing rate, and temperature).
  • Fluid in.
  • Food eaten.
  • Fluid out.
  • When your bowel first starts working.
  • Pain assessment.
  • Number of walks.
  • Time spent out of bed.
  • Vaginal bleeding.
  • Wound checks.

Please remember to tell us about everything that you eat and drink and what you pass.

Whilst you are in hospital you will be asked to participate in maintaining a ‘daily diary’ (provided by the ward), so that you 
can keep a record of how well you are managing, in particular with diet and exercise after surgery. This will also help us monitor your progress.

Decisions regarding patient care are at the discretion of your consultant. Patients who are no longer able to follow the structure of the programme will revert to a traditional plan of care.

 

When you leave hospital

Complications should not happen very often, but it is important that you know what to look out for. During the first two weeks after surgery, if you are worried about any of the following (see information on the following page), please phone the telephone numbers on this leaflet. You should be able to reach a member of staff at any time. If you cannot contact the people listed, then ring your GP or NHS 111. 

If you have had surgery on your bowel, the hospital team will phone you at home initially to check on your progress. In between these times if you have any concerns, you can contact them on the numbers provided. 

Abdominal Pain

It is not unusual to suffer pains during the first week following surgery. Continue taking your painkillers regularly. 
If you have severe pain lasting more than 1-2 hours or have a fever and feel generally unwell, you should contact 
us on the telephone numbers provided

Your wound

The Ward nurses will remove your wound dressing before discharging you home. If you have had keyhole surgery you will have dissolvable stitches and glue over the top. You may continue to take showers or baths. 

For surgery where a larger incision has been needed, either dissolvable stitches are used, or a stitch that needs to be removed. This can be taken out with the GP practice or district nurse about 5-7 days after surgery, and we will discharge you with a plan for this. It is not unusual for your wounds to be slightly red and tender during the first 1-2 weeks. You may also notice bruising. 
 

Please let us know if your wound:

  • Becomes more red, painful or swollen.
  • Starts to discharge fluid / pus. 

Vaginal bleeding or discharge 

It is not uncommon to have some vaginal discharge or bleeding after surgery. Light bleeding like the end of a period is normal for a few weeks after surgery. This can be red, pink or brown in colour. If your bleeding is heavy, like a period, or with blood clots, you should contact the ward directly. If you have an unpleasant smell to the discharge this could indicate an infection. Please contact your GP or call Cotswold Ward for advice. Bleeding/discharge can continue for 10 days to 2 weeks following surgery, and should then settle. No tampons should be used during this time and intercourse should be avoided for 6-8 weeks.

Your bowels 

In the early stages following surgery, your bowel habits may change and may either become loose or constipated. Make sure you eat regular meals 3 or more times a day, drink adequate amounts, and take regular walks the first two weeks after your operation. 

Please seek advice from your GP if you are experiencing prolonged constipation.

Passing urine

Sometimes after surgery you may experience the feeling of a full bladder. This usually resolves, however if you experience any of the following problems please contact your GP, or ring Cotswold Ward for advice:

  • Bladder pain or discomfort.
  • If you have excessive stinging when passing urine, you may have an infection which will require treatment. 

Diet

A balanced, varied diet is recommended and particularly eating 3 or more times a day. If you are finding it difficult to eat it is still important to obtain an adequate amount of protein and calories to help your body heal. You may benefit from having 3-4 high protein, high calorie drinks such as Build-up or Complan (available in supermarkets and chemists) to supplement your food. It is important to drink plenty of water.

Helpful suggestions 

  • Eat small nourishing snacks between meals.
  • Try not to skip meals, have a snack or nourishing drink if you cannot manage a main meal. 
  • Have nourishing drinks during the day. Avoid drinks up to 30 minutes before meals, as they may fill you up.
  • Have a selection of easy-to-prepare foods in case you do not feel like cooking.
  • Make use of your freezer and cupboards to store convenience foods.
  • Aim to try and have 5 daily portions of fruit and vegetables to ensure a good vitamin and mineral intake. 

Exercise

We encourage activity from day one following surgery. You should plan to undertake regular exercise several times a day and gradually increase during the 4 weeks following your operation until you are back to your normal level of activity. The main restriction we place on exercise is that you do not undertake heavy lifting 4-6 weeks following your surgery. If you are planning to restart a routine exercise such as jogging or swimming we suggest that you wait until 2 weeks after surgery and start gradually. Common sense will guide your exercise and rehabilitation; in general if the wound is still uncomfortable modify your exercise. Once the wounds are pain free you can undertake most activities.

Work

When you return to work will depend on the type of operation you have had, your surgeon will guide you on this. Many 
people are able to return to work within 2 - 4 weeks following their surgery. If your job involves lots of lifting we suggest you ask your employer to give you lighter duties until you are fully recovered.

Driving

It is advised that you do not drive until you are confident that you can drive safely. Usually this is when you are doing most of your normal activities. In general this will be 4 weeks after surgery. It is important that any pain has resolved sufficiently to enable you to perform an emergency stop. You should contact your insurance company to check their terms or you may not be fully insured.

Resuming intercourse (sex) 

For certain types of operations, it is advisable to avoid intercourse for 6-8 weeks following surgery, please check 
with your surgeon. We advise that you wait until any vaginal bleeding has stopped. 

Naturally if you are not wishing to get pregnant contraception is important to consider, as you will continue to ovulate after your surgery, and you can fall pregnant quickly. 

Hobbies and activities

In general it is advised that you take up your hobbies and activities as soon as possible again after surgery. It enables you to maintain your activity and will benefit your convalescence. We would not advise restricting these unless they cause significant pain or involve heavy lifting within the first 6 weeks following surgery.

Medications

You may continue with your normal medicines unless directed to stop by your doctor. You will be given a new supply of these if you do not have enough at home. You will also be given pain killers and any other medicines required, to take home. 

Clinic follow up appointments 

Not all patients require an appointment after their surgery if your Consultant thinks a follow-up appointment is needed, this will be sent through the post.

Follow up appointments allow the team to see how you are and talk through any further treatment. 

If you have had an operation on your bowel, you will be contacted at home via telephone after your operation by the nursing team. We also encourage you to contact the specialist nurse or ward if you are experiencing problems.

 

Further information

Fitter Better Sooner:
Preparing for surgery – Fitter Better Sooner | The Royal College of Anaesthetists (rcoa.ac.uk)

Endometriosis UK Charity:
Your laparoscopy | Endometriosis UK (endometriosis-uk.org)


 

 

 

 

 

 

 

 

 

 

Page last reviewed December 2023

Page due for review December 2026

Gynaecology

Bristol NHS Group Merger Plans

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Bristol NHS Group – a partnership between North Bristol NHS Trust and University Hospitals Bristol and Weston NHS Foundation Trust – is taking the next step in its journey to improve care for people across Bristol, North Somerset and South Gloucestershire. 

Since the formation of Bristol NHS Group in April 2025, guided by our Group Clinical Strategy, our clinical services have increasingly worked as single teams, demonstrating the benefits of collaboration, shared learning and unified leadership. Now the two Trusts are proposing to become a single, merged organisation, with a target date of summer 2026.

With 28,000 staff and a combined turnover of over £2.2 billion, the proposed merger creates an exciting future that brings together the best of both organisations. Delivering better outcomes for our patients, more opportunities for our people, fairer care for our population, and best value for the public purse.

One organisation, many strengths

Becoming a single organisation will make it easier to provide the high‑quality, equitable care we strive to deliver. It will:

  • reduce variation in waiting times
  • improve access to specialist services
  • ensure patients experience smoother, more coordinated care

Early work through our Group Clinical Strategy has already shown the benefits of working in partnership. For example, cardiology services have reduced waiting times by operating as one team across the Group. 

The merger also strengthens our ability to invest in the future, including modern digital systems, research and innovation, and the shift towards more preventative, community‑based care. It supports the ambitions of the NHS 10‑Year Plan, with a strong focus on prevention, early intervention and tackling health inequalities.

The Four Ps

Building on the strong foundations of Bristol NHS Group, exploring a merger is therefore both clinically led and patient focused. It is designed to remove remaining structural barriers and deliver improvements to care and services at greater scale and pace.

These improvements will be delivered across what we call our 'Four Ps':

  • faster more equitable access to safer care for our patients, with improved outcomes for all. 
  • greater opportunities for our people, with clearer career pathways, stronger wellbeing and leadership support, and a shared culture built on belonging and collaboration. 
  • fairer, more consistent care for our population, with services closer to home and a renewed focus on prevention. 
  • a more sustainable NHS that can reinvest savings from reduced duplication back into frontline care, delivering best value for the public purse

Next steps

The proposal to merge is now going through a formal national assurance process, and is subject to approvals from Bristol NHS Group Board, Council of Governors, NHS England and the Secretary of State. Staff, patients and partners will continue to be involved throughout this process.

What remains constant is our commitment to deliver safer, more consistent, equitable care for anyone and everyone that needs it.

Patient involvement

To make sure that our patients and communities have a meaningful voice in shaping the future of local healthcare services, we have established a Community Participation Group (CPG).

The CPG provides independent oversight, advice and input on how patients and the public are involved in the development of services. It aims to be representative of our communities, including Patient and Carer Partners and Governors, and creates opportunities for new voices to be heard.

 

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Breast Cancer and Genetics

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What is Genetic Testing and how might it affect me?

What are the potential results of this test and what might they mean?

I am male and I have breast cancer does this affect me?

What are the health risks associated with this gene alteration?

What else should I know about getting a genetic test?

Are certain racial or ethnic populations at greater risk?

My Role in Research

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Clinical research helps us to find the best possible care options for our patients. Our dynamic research teams include an array of research support staff who help us to deliver over 500 research studies every year. Our 'My Role in Research' series aims to delve a little deeper into these roles...

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Dr John Pauling - Rheumatology

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GMC number: 6054876

Dr John Pauling


Year & location of first qualification: 2002, Nottingham University

Specialty: Rheumatology

Clinical interests: Systemic sclerosis & Raynaud’s phenomenon, Digital vasculopathy in autoimmune rheumatic diseases, Connective Tissue Diseases, Interstitial Lung Disease and Pulmonary Arterial Hypertension
Secretary: Pamela Stone   
  
Dr John Pauling BMedSci BMBS FRCP (Rheum) PhD 
North Bristol NHS Trust and Honorary Senior Lecturer in the School of Translational Sciences at the University of Bristol

Dr John Pauling is a consultant rheumatologist at North Bristol NHS Trust and Honorary Senior Lecturer in the School of Translational Sciences at the University of Bristol. John was awarded the Arthritis Research Campaign Medal before qualifying from Nottingham University Medical School in 2002. In 2009 he was awarded the Dando fellowship, jointly funded by the Raynaud’s & Scleroderma Association and Royal College of Physicians. His PhD research helped John to develop an interest in outcome measures in systemic sclerosis (SSc) research, particularly in relation to peripheral microvascular dysfunction in scleroderma. He has developed and validated new methods for assessing digital vasculopathy including patient reported outcome instruments and laser-derived methods in Raynaud’s phenomenon (RP) and systemic sclerosis. John is a member of the EULAR Microcirculation study group and has contributed to recent initiatives of the UK Scleroderma Study Group. John has published over 130 peer-reviewed journal articles and several book chapters in the field of peripheral vascular disease and systemic sclerosis (h-index 30). He has presented at multiple international meetings.

Dr John Pauling sits on the executive committee of the Scleroderma Clinical Trials Consortium (SCTC) and leads the SCTC Vascular Working Group that is currently undertaking work to develop novel outcome measures for Raynaud’s phenomenon and digital ulcer disease in systemic sclerosis. He co-chairs the OMERACT systemic sclerosis special interest group. He leads the Raynaud’s taskforce for an NIH initiative to appraise outcome measures suitable for assessment by the FDA when considering clinical trials of SSc-RP. He also co-chairs the SCTC Industry Roundtable bringing together industry representatives and international scleroderma investigators to advance clinical trial design in SSc.

Related Links - Rheumatology Pauling

Conservative management of upper limb fractures in frailty

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2021:  BGS Autumn meeting platform presentation abstract

805 Clinical quality – clinical effectiveness

L Shaw; T Maggs; P Braude; D Shipway; S Srivastava; M Kelly 

Introduction

Upper limb fractures are the second most common fracture requiring admission to hospital after hip fracture [Jennison, 2019].  At 1-year 20.5% have died, compared to 29.5% in hip fracture [Wiedl, 2021].     Local Problems:  At North Bristol Trust most patients with upper limb fractures and a Clinical Frailty Score ≥ 5 are managed non-operatively on medical wards. Local service evaluation identified a long length of stay of 23 days.    Case note review revealed:  ∙ Delayed transfers of care (DTOCs) had been managed non-weight bearing in slings for 4-6 weeks.  ∙ Non-weight bearing status resulted in DTOC due to declined access to social care and rehabilitation due to perceived health needs.  ∙ A high rate of hospital-acquired complications and failure to rehabilitate.  ∙ Breakdown in interdisciplinary communication and ownership across the pathway.     

Methods

A multidisciplinary QI project was commenced.  Using local data through business analytics, clinician and patient feedback, a new Trust guideline was developed for older people with frailty and upper limb fractures. Data collected determined average length of stay before and after implementation of the service change.  A standard process control chart was created monitoring the effect of the changes in the pathway. The multidisciplinary team met regularly to make alterations during implementation.    The resulting intervention included:  ∙ Removal of functional restrictions; allow free use of limb as comfort permits.   ∙ Simplified slings and minimised light weight casts.  ∙ Proactive integration of orthopaedic plan into CGA documentation.  ∙ Proactive interdisciplinary communication across pathways.  ∙ Patient information leaflets.     

Results

Pre-intervention average length of stay was 23 days. Post-intervention was 14 days.     

Conclusion

Proactive, structured management of upper limb fractures in people with frailty is associated with significant reduction in acute hospital length of stay.  Next steps include a business case for a frailty trauma specialist therapist embedded into medicine.

Addendum 2023

Additional thanks for ongoing support from Tahid Alam,  Alasdair Bott, Andrew Riddick, Frances Verey, Lynn Hutchings, Nathanael Ahearn