The laboratory component of the Avon Cervical Screening Programme is based in the department. The workload of the cytology laboratory is one of the largest in the South West region.  A Service Agreement with NHS Bristol is in place, an agreement that covers not only Cytology but also Histology and Colposcopy.  The department was the first laboratory in the UK to undertake 100% of its primary screening using molecular techniques for detection of High Risk HPV within the Cervical Screening Programme.

Severn Pathology is also host to the South West Regional Cytology Training Centre although this unit is managed separately to the diagnostic laboratory.