C1 Esterase Inhibitor

Sample type: Serum

Test name: C1 Esterase Inhibitor

Condition / Indication: Diagnosis and monitoring of C1 esterase inhibitor

Special precautions & notes: Very low levels seen in hereditary angioedema. (Rare; 1/50000). C4 is always low in acute episodes. Freeze within 24 hours of venepuncture. Samples must be transported frozen to NBT.

Reference range: Immunochemical 0.21-0.38g/L, Functional >70%

Container: Serum (Gold top)

Ideal volume (mL): 2 mL

Referred outside NBT for analysis? No

Discipline: Immunology

Turnaround time: 14 days

Information for Laboratories referring samples for analysis at NBT:

Minimum volume 200ul serum.
Freeze within 24 hours of venepuncture.
Sample must be transported frozen to NBT.

Method:

Immunochemical - Turbidimetry. Functional - colourimetric