Sample type: Serum

Test name: Centromere Antibody

Condition / Indication: Systemic sclerosis 10-30%; Limited Scleroderma (CREST) 70-95%

Container: Serum (Gold top)

Ideal volume (mL): 2 mL

Referred outside NBT for analysis? No

Discipline: Immunology

Section: Autoimmunity/Allergy

Turnaround time: 7 working days

Method:

Primary care- first line FEIA (Fluorescence enzyme immunoassay)
Secondary care - first line Indirect immunofluorescence

Further information: UK NEQAS for Antibodies to Nuclear and Related Antigens