Sample type: Serum

Test name: Cryoglobulin

Condition / Indication: Monoclonal cryoglobulin (Type 1) associated with lymphoma/Myeloma. Mixed cryoglobulins (Type II) seen in auto-immune disease, lymphoma or infection and show rheumatoid factor activity.  Polyclonal cryoglobulins (Type III) associated with Hepatitis C infection.

Special precautions & notes: Request MUST be discussed with laboratory prior to taking sample. 
Special procedures and transport at 37°C essential.

Reference range: Negative/Positive. Positives: Cryoglobulin type and quantity reported (g/l)

Container: Serum (Gold top)

Ideal volume (mL): Discuss with Laboratory

Referred outside NBT for analysis? No

Discipline: Immunology

Section: Immunochemistry/Proteins (0117 414 8379)

Turnaround time: 10 working days

Method:

Serum Immunofixation Electrophoresis

Further information: EQA: UK NEQAS Cryoglobulin