Sample type: Serum

Test name: Flucloxacillin

Condition / Indication: Requesters have found these assays to be of value in patients transferring from iv to oral therapy, cases of suspected neurotoxicity, and patients with severe sepsis and renal failure.

Advance warning: Please telephone at least one day in advance of the sample.

Special precautions & notes: Samples should NOT be sent by post since the drug is liable to degradation. Send courier, frozen or on ice.

Sample required: Approx. 1-2mL of separated serum (the minimum acceptable is 100µL). Samples must be sealed and packed to conform to current regulations. Leaking samples may not be processed.

Timing of samples: We recommend a pre dose sample and a post dose sample, taken either 1 hour after the end of iv/im administration or 2 hours after oral administration.

Test information required: • Patient name, sex and age
• Laboratory number
• Dosage, frequency and timing of samples
• Clinical Summary
• Other medications (essential)
• Address for report
• Phone (fax if preferred) number for report or email address for an electronic copy
• Contact name
• Appropriate hazard warnings

Results: Results will be telephoned/faxed or emailed on the day of receipt for samples received between 9 am and 3 pm Monday to Friday. A written confirmation report will be sent by post.

Reference range: There are too many dose regimens used to give single guideline ranges for this particular assay and interpretations of levels needs to be patient specific.

Container: Serum (Gold top)

Referred outside NBT for analysis? No

Discipline: Antimicrobial Reference Laboratory

Turnaround time: <3 days