Sample type: Serum

Test name: Free Light Chains

Special precautions & notes: Accepted only after consultation with Haematologists

Reference range: Age <70, eGFR 60+ (CKD 1&2): Kappa FLC 6.3-39.0 mg/L, Lambda FLC 5.9-36.7 mg/L, K:L ratio 0.44-2.16;
Age ≥70, eGFR 60+ (CKD 1&2): Kappa FLC 7.0-55.8 mg/L, Lambda FLC 6.4-48.0 mg/L K:L ratio 0.46-2.59;
All ages, eGFR 45-59 (CKD 3a): Kappa FLC 7.8-83.6 mg/L, Lambda FLC 7.3-65.1 mg/L K:L ratio 0.46-2.62;
All ages, eGFR 30-44 (CKD 3b): Kappa FLC 8.8-103.3 mg/L, Lambda FLC 8.2-73.2 mg/L K:L ratio 0.48-3.38;
All ages, eGFR <30 (CKD 4&5): Kappa FLC 11.7-265.1 mg/L, Lambda FLC 12.6-150.9 mg/L K:L ratio 0.54-3.30.

Container: Serum (Gold top)

Ideal volume (mL): 2 mL

Referred outside NBT for analysis? No

Discipline: Immunology

Section: Immunochemistry/Proteins

Turnaround time: 7 working days

Method:

Immunoturbidimetry

Further information: EQA UK NEQAS Monoclonal protein scheme