Sample type: Blood spot

Test name: Newborn Screen a.k.a. guthrie test

Condition / Indication: Newborn Blood spot screen

Special precautions & notes: Currently, screens for PKU, MCADD, IVA, HCU, MSUD, GA1, congenital hypothyroidism, Cystic Fibrosis and sickle cell disease are performed. Please see www.nbt.nhs.uk/severn-pathology-new/pathology-services/clinical-biochemistry/newborn-screening for further information including sample requirements and expected turn around times.

Reference range: Suspected' results reported immediately to the appropriate clinician (Health Visitor and GP are also informed). Other results including 'Not suspected' reported to the appropriate Child Health Record Department.

Container: Bloodspots on a newborn screening card

Ideal volume (mL): 4x Spots

Referred outside NBT for analysis? No

Discipline: Clinical Biochemistry

Section: Newborn Screening

www.nbt.nhs.uk/severn-pathology-new/pathology-services/clinical-biochemistry/newborn-screening

Method:

Tandem Mass Spectrometry (PKU, MCADD, IVA, HCU, MSUD, GA1), Immunoassay (CHT, CF), HPLC with IEF to confirm (Sickle).